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Description |
Unit |
Price
(VAT별도) |
납기 |
재고 |
DataSheet |
주문/견적 |
| LCA-25-148186 |
GTX26679 |
Anti-HIF1 alpha panel combo pack Antibody, Unconjugated/1 kit/Human, Mouse, Rat, Ferret, Rabbit, Sheep/Mouse |
1/EA |
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문의 |
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Subject
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Anti-HIF1 alpha panel combo pack Antibody, Unconjugated |
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Description
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1 kit / Human, Mouse, Rat, Ferret, Rabbit, Sheep/Mouse |
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Clonality
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Poly |
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Company
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GeneTex |
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Application
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Western blot / Immunoblot |
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Conjugation
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Unconjugated |
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Immunogen
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HIF1 alpha panel |
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Contents
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Description: | Manufacturer | GeneTex Inc. | | Quantity | 1 kit | | Reactivity | Human, Mouse, Rat, Ferret, Rabbit, Sheep | | Applications | Western blot / Immunoblot | | Clone | Please look at individual data sheets for these products for | | PDF datasheet | view | | Shipping to | Europe only | | Immunogen | GTX30105 HIF1 alpha mouse monoclonal antibody. Immunogen = Fusion protein containing amino acids 432-528 of human HIF1 alpha. GTX26274 HIF1 alpha mouse monoclonal antibody. Immunogen = Fusion protein containing amino acids 432-528 of human HIF1 alpha. G | | Product Type | Antibodies | | Storage | Keep as concentrated solution. Store at 4 | |
| Format | State: Liquid | | ? | Purity: Please look at individual data sheets for these products for detailed information. | | ? | Purification: Please look at individual data sheets for these products for detailed information. | | ? | Buffer System: Please look at individual data sheets for these products for detailed buffer information. | |
| Specificity | GTX30105 - Reacts with Human, Sheep, Mouse, Rat, Rabbit and Ferret. Does NOT react with Cow. GTX26274 - Reacts with Human. GTX30124 - Reacts with Human and Rat. GTX26489 - Reacts with Human. GTX16535 - Reacts with Human and Mouse. Not tested in other species. | | Application | WB | | Background | HIF1 (hypoxia inducible factor 1) is a heterodimer consisting of an alpha and a beta subunit, both belonging to the basic helix loop helix Per-aryl hydrocarbon receptor nuclear translocatorSim (PAS) family of transcription factors. HIF1 is a key component of a widely operative transcriptional response activated by hypoxia, cobaltous ions, and iron chelation. HIF1 activates transcription of hypoxia-inducible genes, including those encoding: erythropoietin, vascular endothelial growth (VEGF), heme oxygenase 1, inducible nitric oxide synthase,and the glycolytic enzymes aldolase A, enolase 1,lactate dehydrogenase A, phosphofructokinase I, and phosphoglycerate kinase 1. The C-terminal of HIF 1 alpha binds to p300. p300/CBP-HIF complexes participate in the induction of hypoxia-responsive genes, including VEGF. | |
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