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Description |
Unit |
Price
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납기 |
재고 |
DataSheet |
주문/견적 |
| LCA-23-310479 |
NB100-2014 |
Acetylcholinesterase Antibody [HRP]//Bovine/Goat |
1/EA |
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문의 |
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Subject
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Acetylcholinesterase Antibody [HRP] |
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Description
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/ Bovine/Goat |
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Clonality
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Poly |
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Company
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Novus biologicals |
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Application
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ELISA, IF, IHC-P, Western Blot |
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Conjugation
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Immunogen
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Contents
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Description:Summary: | Species: | Bv | | Applications: | WB, IF, IHC-Fr, ELISA | | Clonality: | Polyclonal | | | Gene: | ACHE | | Purity: | IgG purified | | Host: | Goat | | | Specificity: | Acetylcholine Esterase | | Publications: | Antibody has not yet been mentioned in a publication. | Details: | Conjugate: | HRP | | Isotype: | IgG | | Immunogen: | Acetyl Cholinesterase [Bovine Erythrocytes] | Gene Symbol: ACHE | Related Genes: | CHAT, BCHE, CAT, SH2D3C, GLYAT, OP, VIP, TH, TAC1, NGF, G4, NPY, AFP, APP, PNPLA6, ACHR, ACE, DLD, GSTP1, LAMC2, GSTK1, SLCO6A1, SST, CA1, ALB, SLC18A3, NT5E, GFAP, BDNF, POMC, CA3, TRIM26, SOD1, LIPG, CALCA, CHRNA4, A12, S100A12, GPI, GSR | Background: Acetylcholinesterase hydrolyzes the neurotransmitter, acetylcholine at neuromuscular junctions and brain cholinergic synapses, and thus terminates signal transmission. It is also found on the red blood cell membranes, where it constitutes the Yt blood group antigen. Acetylcholinesterase exists in multiple molecular forms which possess similar catalytic properties, but differ in their oligomeric assembly and mode of cell attachment to the cell surface. It is encoded by the single ACHE gene, and the structural diversity in the gene products arises from alternative mRNA splicing, and post-translational associations of catalytic and structural subunits. The major form of acetylcholinesterase found in brain, muscle and other tissues is the hydrophilic species, which forms disulfide-linked oligomers with collagenous, or lipid-containing structural subunits. The other, alternatively spliced form, expressed primarily in the erythroid tissues, differs at the C-terminal end, and contains a cleavable hydrophobic peptide with a GPI-anchor site. It associates with the membranes through the phosphoinositide (PI) moieties added post-translationally. Species: | Reactivity: | Cross-reacts with Cow. Not yet tested in other species. | Applications: | Uses: | Suitable for immunoblotting (western or dot blot), ELISA (1:2,000 to 1:10,000), immunoperoxidase electron microscopy and immunohistochemistry as well as other peroxidase-antibody based enzymatic assays. | | Dilutions: | ELISA, Immunohistochemistry-Frozen, immunofluorescence, Western Blot | Packaging: | Buffer: | 0.01M Na phosphate, 0.25M NaCl, pH7.6, 0.05% Na azide, 0.01% Thimerisol, 15mg/ml BSA | | Storage: | Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles. | | Preservative: | 0.01% Gentamicin Sulfate | | Limitations: | This product is for research use only and is not approved for use in humans or in clinical diagnosis. Products are guaranteed for 6 months from date of receipt, except for peptides and proteins which are guaranteed for 3 months. | |
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