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Description |
Unit |
Price
(VAT별도) |
납기 |
재고 |
DataSheet |
주문/견적 |
| LCA-23-310428 |
NB110-85481 |
ABCB5 Antibody//Human/Rabbit |
1/EA |
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문의 |
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Subject
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ABCB5 Antibody |
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Description
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/ Human/Rabbit |
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Clonality
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Poly |
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Company
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Novus biologicals |
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Application
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ELISA, Western Blot |
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Conjugation
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Immunogen
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Contents
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Description:Summary: | Species: | Hu | | Applications: | WB, ELISA | | Clonality: | Polyclonal | | | Gene: | ABCB5 | | Purity: | Affinity purified | | Host: | Rabbit | | | Specificity: | This antibody is specific for human ABCB5 protein. A BLAST analysis was used to suggest partial cross-reactivity with ABCB5 from monkey (85% homology), rat (68% homology) and mouse (62% homology) sources. Cross-reactivity with ABCB5 from other sources has not been determined. | | Publications: | Antibody has not yet been mentioned in a publication. | Details: | Immunogen: | This affinity purified antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide corresponding to residues corresponding to an internal region of human ABCB5. | Gene Symbol: ABCB5 | Entrez: | 340273 (Human) | | Related Genes: | ABCA1, ABCB1, RFC2, RFC1, ATP6V0A1, RFC4, ABCC8, ABCG2, CFTR, ABCC1, APOA1, PPARG, KCNJ11, MSH3, ABCB4, MDM4, TBC1D9, ABCC2, ABCD1, ABCE1, PPARA, ABCC6, ABCC9, SUR2A, ABCA3, ABCF1, ABCB8, EXOSC10, ABCC3, ABCB6, ABCD3, ABCB11, ABCC10, MVP, KLRD1, ABCB7, KLRC1, LRP1, S100A12, KCNJ8 | Background: ATP-Binding Cassette proteins comprise a superfamily of transporters with a wide variety of substrates. ABCB5 is a novel member of the human P-glycoprotein family. It functions as a determinant of membrane potential and regulator of cell fusion in physiologic skin progenitor cells. Cell fusion is thought to contribute to tissue differentiation. ABCB5 is predominantly expressed in melanoma cells and is a novel molecular marker for a distinct subset of chemoresistant stem cell phenotype-expressing tumor cells among human epidermal melanocytes. It has been identified as a novel drug transporter in human malignant melanoma. ABCB5 is a rhodamine efflux transporter. This antibody product is intended to be used to confirm cellular localization and expression level of ABCB5. Species: | Reactivity: | Reacts with Human. monkey 85% sequence identity with monkey, 68% with rat and 62% with mouse proteins. | Applications: | Uses: | This antibody is useful for Western Blot and ELISA. Expect a band approximately 117 kDa in size corresponding to ABCB5 by western blotting in the appropriate cell lysate or extract. | | Dilutions: | ELISA 1:80000-1:85000, Western Blot 1:10000, | | Concentrations: | 0.74 mg/ml | | Positive Controls: | 1 positive controls | Packaging: | Buffer: | 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2 | | Storage: | Store at -20C. Avoid freeze-thaw cycles. | | Preservative: | 0.01% Sodium Azide | | Limitations: | This product is for research use only and is not approved for use in humans or in clinical diagnosis. Products are guaranteed for 6 months from date of receipt, except for peptides and proteins which are guaranteed for 3 months. | |
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