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| Cat. No |
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Description |
Unit |
Price
(VAT별도) |
납기 |
재고 |
DataSheet |
주문/견적 |
| LCA-23-310445 |
NB400-110B |
ABCG8 Antibody [Biotin]//Human, Mouse(-)/Rabbit |
1/EA |
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문의 |
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Subject
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ABCG8 Antibody [Biotin] |
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Description
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/ Human, Mouse(-)/Rabbit |
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Clonality
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Poly |
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Company
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Novus biologicals |
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Application
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Western Blot |
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Conjugation
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Immunogen
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Contents
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Description:Summary: | Species: | Mu(-), Hu | | Applications: | WB | | Clonality: | Polyclonal | | | Gene: | ABCG8 | | Purity: | Immunogen affinity purified | | Host: | Rabbit | | | Specificity: | Specific for ABCG8. | Details: | Conjugate: | Biotin | | Immunogen: | A synthetic peptide from the N-terminal region of human ABCG8 protein. | | Localization: | Integral membrane protein; multi-pass membrane protein | Gene Symbol: ABCG8 | Entrez: | 64241 (Human) | | Swiss Prot: | Q9H221 (Human) | | Related Genes: | ABCG5, ABCA1, NPC1L1, ABCB4, LXR, ABCB11, CYP7A1, BAT5, BAT4, ABCG1, SCARB1, ABCC1, LDLR, NR1H4, ABCC2, ABCC3, ABCG2, NR0B2, SOAT2, KLHL1, PPARA, APOB, SLC10A1, NR1H3, VLDL, MSH3, INS, MTTP, MDM4, APOA1, RFC2, RFC1, ABCA4, ATP6V0A1, RFC4, MARCKSL1, CYP27A1, GPR177, SREBF2, SREBF1 | Background: ATP-binding cassette (ABC) transporter genes are involved in the regulation of the amount of dietary cholesterol retained in the body. ABCG8, expressed at high levels in the liver and intestine, normally cooperates with ABCG5 to limit intestinal absorption and promote biliary excretion of sterols. The mutated form of this transporter can lead to sterol accumulation and atherosclerosis or sitosterolemia, a rare autosomal recessive disorder, characterized by hyperabsorption of sterols and the inability to excrete sterols into bile. Species: | Reactivity: | Human. Does not appear to cross react with mouse. | Applications: | Uses: | It does not appear to be applicable in immunohistochemistry. | | Dilutions: | Western Blot 1:500 | | Concentrations: | 1.0 mg/ml | | Conjugated Ab's: | 4 conjugated antibodies | Packaging: | Buffer: | PBS | | Storage: | Store at 4C. Do not freeze. | | Preservative: | No Preservative | | Limitations: | This product is for research use only and is not approved for use in humans or in clinical diagnosis. Products are guaranteed for 6 months from date of receipt, except for peptides and proteins which are guaranteed for 3 months. | |
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