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Description |
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Price
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납기 |
재고 |
DataSheet |
주문/견적 |
| LCA-23-310474 |
NB100-1958 |
Acetylated Lysine Antibody [HRP]//ELISA, IF/Rabbit |
1/EA |
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문의 |
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Subject
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Acetylated Lysine Antibody [HRP] |
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Description
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/ ELISA, IF/Rabbit |
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Clonality
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Poly |
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Company
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Novus biologicals |
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Application
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Conjugation
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Immunogen
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Contents
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Description:Summary: | Applications: | WB, IP, IF, ELISA | | Clonality: | Polyclonal | | | Purity: | Immunogen affinity purified | | Host: | Rabbit | | | Specificity: | Detects proteins containing acetylated lysine residues in SDS-PAGE immunoblots. | | Publications: | Antibody has not yet been mentioned in a publication. | Details: | Conjugate: | HRP | | Isotype: | IgG | | Immunogen: | Acetylated KLH conjugates. | Background: Post-translational modifications of proteins play critical roles in the regulation and function of many known biological processes. Proteins can be post-translationally modified in many different ways, and a common posttranscriptional modification of Lysine involves acetylation (1). The conserved amino-terminal domains of the four core histones (H2A, H2B, H3 and H4) contain lysines that are acetylated by histone acetyltransferases (HATs) and deacetylated by histone deacetylases (HDACs) (2). Protein posttranslational reversible lysine Nå-acetylation and deacetylation have been recognized as an emerging intracellular signaling mechanism that plays critical roles in regulating gene transcription, cell-cycle progression, apoptosis, DNA repair, and cytoskeletal organization (3). The regulation of protein acetylation status is impaired in the pathologies of cancer and polyglutamine diseases (4), and HDACs have become promising targets for anticancer drugs currently in development (5). Species: | Reactivity: | Cross reacts with multiple species. | Applications: | Uses: | ELISA, Immunofluorescence, Western Blot and Immunoprecipitation | | Dilutions: | ELISA , immunofluorescence , immunoprecipitation , Western Blot | | Concentrations: | 0.25 mg/ml | Packaging: | Buffer: | PBS, 0.01% NaN3 | | Storage: | Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles. | | Preservative: | 0.01% Sodium Azide | | Limitations: | This product is for research use only and is not approved for use in humans or in clinical diagnosis. Products are guaranteed for 6 months from date of receipt, except for peptides and proteins which are guaranteed for 3 months. | |
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