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| Cat. No |
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Description |
Unit |
Price
(VAT별도) |
납기 |
재고 |
DataSheet |
주문/견적 |
| LCA-23-310475 |
NB500-109 |
Acetylated Lysine Antibody (11A1)//Alligatorl/Mouse |
1/EA |
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문의 |
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Subject
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Acetylated Lysine Antibody (11A1) |
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Description
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/ Alligatorl/Mouse |
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Clonality
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Mono |
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Company
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Novus biologicals |
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Application
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ELISA, IHC-P, Western Blot |
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Conjugation
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Immunogen
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Contents
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Description:Summary: | Species: | All | | Applications: | WB, IHC, ELISA | | Clonality: | Monoclonal | | | Purity: | Ascites | | Host: | Mouse | | | Specificity: | This reacts with the Ne-acetyl lysine, N-acetyl putrescine and acetylated histones. There is no cross reaction with either propionyl lysine or butyryl lysine. | | Publications: | Antibody has not yet been mentioned in a publication. | Details: | Clone: | 11A1 | | Isotype: | IgG1 Kappa | Background: Nucleosome composition varies considerably from one chromosomal domain to the next, with a major variable being histone acetylation. The level of histone acetylation also correlates directly with the transcriptional activity of a particular domain. Histone acetylation destabilizes the nucleosome structure and renders the DNA more accessible to transcription factors. This destabilization is the result of the reduction in the capacity of the acetylated N-terminal tails to stabilize the path of DNA in the nucleosome through charge neutralization. Recent studies of the several enzymes involved in acetylation and deacetylation of histone residues have revealed a possible relationship between gene transcriptional activation, histone acetylation, and tumor suppressor function. Species: Applications: | Uses: | This antibody is useful for ELISA, Western blot, and immunohistochemistry. | | Dilutions: | ELISA - 1:5,000-1:50,000 , immunohistochemistry - 1:500-1:5,000, Western Blot - 1:500-1:5,000, | Notes: Reconstitute in 200 ul of distilled water. Packaging: | Buffer: | Lyophilized Mouse ascites. | | Storage: | Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles. | | Preservative: | No Preservative | | Limitations: | This product is for research use only and is not approved for use in humans or in clinical diagnosis. Products are guaranteed for 6 months from date of receipt, except for peptides and proteins which are guaranteed for 3 months. | |
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