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| Cat. No |
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Description |
Unit |
Price
(VAT별도) |
납기 |
재고 |
DataSheet |
주문/견적 |
| LCA-23-310486 |
NB100-55258 |
Acinus Antibody//Human/Rabbit |
1/EA |
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문의 |
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Subject
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Acinus Antibody |
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Description
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/ Human/Rabbit |
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Clonality
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Poly |
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Company
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Novus biologicals |
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Application
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IP, Western Blot |
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Conjugation
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Immunogen
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Contents
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Description:Summary: | Species: | Hu | | Applications: | WB, IP | | Clonality: | Polyclonal | | | Gene: | ACIN1 | | Purity: | Immunogen affinity purified | | Host: | Rabbit | | Details: | Immunogen: | The epitope recognized by this antibody maps to a region between residue 1291 and the C-terminus (residue 1341) of human apoptotic chromatin condensation inducer 1 using the numbering given in entry NP_055792.1 (GeneID 22985). | Gene Symbol: ACIN1 | Entrez: | 22985 (Human) | | Swiss Prot: | NP_055792.1 (Human) | | Related Genes: | NF2, CAT, ALB, EGF, PRDM10, GLUL, CCK, BBS9, CE, GLYAT, GSTP1, INS, PPA1, RRM2, CD1E, CD82, CYCS, PCNA, CASP3, AVP, CDKN1A, PI3, SOD1, AQP5, AKT1, ME1, G6PD, AKR1A1, PCNT, SERPINF2, PLEC1, RP, GGT1, GCG, PCK2, CREB3L1, ME3, ME2, TNF, TP53 | Background: Chromatin condensation and nuclear fragmentation (CCNF) are the hallmarks of apoptosis. CCNF is triggered by the activation of members of the caspase family, caspase activated DNase (CAD/DFF40), and several novel proteins including AIF and CIDE. A new inducer of chromatin condensation was recently identified and designated Acinus (for apoptotic chromatin condensation inducer in the nucleus). Acinus is cleaved by Caspase 3 and an additional unknown protease generating a small active peptide p17, which causes chromatin condensation in vitro when it is added to purified nuclei. Acinus also induces apoptotic chromatin condensation in cells. Acinus is ubiquitously expressed. Three different spliced forms of Acinus have been identified in human and mouse and designated Acinus L (1341 amino acids), Acinus S (583 amino acids) and Acinus S' (614 amino acids). Species: | Reactivity: | Reacts with Human. | Applications: | Uses: | This antibody is useful for Western Blot and Immunoprecipitation | | Dilutions: | immunoprecipitation 2-5 ul/mg lysate, Western Blot 1:2000-1:10000 | | Concentrations: | 0.2 mg/ml | Packaging: | Buffer: | Tris-buffered Saline containing 0.1% BSA | | Storage: | Store at 4C. Do not freeze. | | Preservative: | 0.09% Sodium Azide | | Limitations: | This product is for research use only and is not approved for use in humans or in clinical diagnosis. Products are guaranteed for 6 months from date of receipt, except for peptides and proteins which are guaranteed for 3 months. | |
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