|
| |
| Cat. No |
Model |
Description |
Unit |
Price
(VAT별도) |
납기 |
재고 |
DataSheet |
주문/견적 |
| LCA-23-310538 |
NB100-584 |
ADAMTS13 Antibody//Human/Rabbit |
1/EA |
|
|
|
|
문의 |
|
|
|
|
|
|
|
Subject
|
ADAMTS13 Antibody |
|
Description
|
/ Human/Rabbit |
|
Clonality
|
Poly |
|
Company
|
Novus biologicals |
|
Application
|
Western Blot |
|
Conjugation
|
|
|
Immunogen
|
|
|
Contents
|
Description:Summary: | Species: | Hu | | Applications: | WB | | Clonality: | Polyclonal | | | Gene: | ADAMTS13 | | Purity: | Affinity purified | | Host: | Rabbit | | | Specificity: | NB100-584 is specific for human ADAM TS13 protein. | Details: | Immunogen: | A synthetic peptide which maps to a region between residues 250 and 350 of human A Disintegrin-like and Metalloprotease (reprolysin type) with Thrombospondin type 1 motif, 13 using the numbering given in entry XP_088414.1 (GeneID 11093). | Gene Symbol: ADAMTS13 | Entrez: | 11093 (Human) | | Swiss Prot: | XP_088414.1 (Human) | | Related Genes: | VWF, ZFP36, CFH, SH3BP4, EGFR, TNF, ADAMTS, ERBB2, THBS1, SLC17A5, CYP19A1, EMP1, VEGFA, RANGAP1, MBC, TYMS, MS4A1, SPZ1, MAPK1, TNFRSF11A, ALB, KLK3, IL6, CRISP2, ZFP36L1, KRT20, IL2, MAPK14, CSF3, TP53, CAT, POMT1, GLYAT, AHSA1, GRAP2, AIMP2, PGR, NPEPPS, PSAT1, PROS1 | Background: This gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motif) protein family. Members of the family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The enzyme encoded by this gene is the von Willebrand Factor (vWF)-cleaving protease, which is responsible for cleaving at the site of Tyr842-Met843 of the vWF molecule. A deficiency of this enzyme is associated with thrombotic thrombocytopenic purpura. Alternative splicing of this gene generates at least four transcript variants encoding different isoforms. Species: | Reactivity: | Human. Other species not tested. | Applications: | Uses: | NB 100-584 has been shown to react with purified recombinant ADAM-TS13 in Western Blot. It has not been tested for reactivity with ADAM-TS13 from native sources, and the antibody is not warranted to have such activity. The suggested WB dilution is for recombinant protein. | | Dilutions: | Western Blot 1:100 - 1:1000 | | Concentrations: | 1.0 mg/ml | Packaging: | Buffer: | Tris-citrate/phosphate buffer, pH 7 to 8 | | Storage: | Store at 4C. Do not freeze. | | Preservative: | Sodium Azide | | Limitations: | This product is for research use only and is not approved for use in humans or in clinical diagnosis. Products are guaranteed for 6 months from date of receipt, except for peptides and proteins which are guaranteed for 3 months. | |
|
|
|
|
