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Model |
Description |
Unit |
Price
(VAT별도) |
납기 |
재고 |
DataSheet |
주문/견적 |
| LCA-23-310540 |
NLS7773 |
ADAMTS4 Antibody//Human/Rabbit |
1/EA |
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문의 |
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Subject
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ADAMTS4 Antibody |
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Description
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/ Human/Rabbit |
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Clonality
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Poly |
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Company
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Novus biologicals |
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Application
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IHC-P, IHC-P |
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Conjugation
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Immunogen
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Contents
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Description:Summary: | Species: | Hu | | Applications: | IHC-P, IHC | | Clonality: | Polyclonal | | | Gene: | ADAMTS4 | | Purity: | Immunogen affinity purified | | Host: | Rabbit | | | Specificity: | A Disintegrin-like and Metalloprotease with Thrombospondin Type 1 Motif 4 (ADAMTS4) | Details: | Immunogen: | Disintegrin-like domain of human | Gene Symbol: ADAMTS4 | Entrez: | 9507 (Human) | | Related Genes: | ADAMTS2, ACAN, ADAMTS5, ADAMTS3, ADAMTS, MMP3, MMP13, MMP-13, ADAMTS1, VCAN, IL1B, ADAMTS-1, MMP9, TNF, TIMP-1, BCAN, MMP1, SLC25A12, IL6, TIMP1, MAPK1, TIMP3, NFKB1, OSM, MMP14, BMP1, TGFB1, ADAM-TS4, COMP, PTGS2, ADAMTS9, NOS2, FMOD, MAPK14, FURIN, ADAM-TS5, MMP17, MMP2, BMP7, PCSK6 | Background: ADAMTS4, also known as aggrecanase-1, is a Metallopeptidase M12B type protease that is responsible for degradation of the articular cartilage protein aggrecan and the brain extracellular matrix proteoglycan brevican. The ADAMTS4 protein contains a signal sequence, a propeptide domain, a catalytic domain, a disintegrin-like motif, and a C-terminal domain with a thrombospondin (TSP) type 1 motif. ADAMTS4 has been implicated in inflammatory joint diseases, and it also may be a factor in the progression of glioma and Alzheimer's disease. ADAMTS4 expression has been documented in normal human brain, cartilage, heart, lung, placenta, muscle, and synovium. ESTs have been isolated from human tissue libraries, including normal brain, lung, pancreas, and skeletal muscle and cancerous breast. Species: Applications: | Uses: | Immunohistochemistry of Formalin fixed paraffin embedded sections. | | Dilutions: | immunohistochemistry , Immunohistochemistry-Paraffin | | Concentrations: | 1.0 mg/ml | Packaging: | Buffer: | Phosphate buffered saline, pH 7.7 | | Storage: | Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles. | | Preservative: | 0.01% Sodium Azide | | Limitations: | This product is for research use only and is not approved for use in humans or in clinical diagnosis. Products are guaranteed for 6 months from date of receipt, except for peptides and proteins which are guaranteed for 3 months. | |
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