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Cat. No |
Model |
Description |
Unit |
Price (VATº°µµ) |
³³±â |
Àç°í |
DataSheet |
ÁÖ¹®/°ßÀû |
LCA-23-310610 |
NB100-65710 |
ACTH Antibody//Human/Rabbit |
1/EA |
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¹®ÀÇ |
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Subject
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ACTH Antibody |
Description
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/ Human/Rabbit |
Clonality
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Poly |
Company
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Novus biologicals |
Application
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IHC-P, IHC-P |
Conjugation
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Immunogen
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Contents
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Description:Summary: Species: | Hu | Applications: | IHC-Fr, IHC-P | Clonality: | Polyclonal | | Gene: | POMC | Purity: | Whole antisera | Host: | Rabbit | | Specificity: | Recognizes human adrenocorticotrophin (ACTH), a 39 amino acid cleavage product from pro-opiomelanocortin (POMC) which elicits a classic glucocorticoid response from the adrenal glands in situations of stress. ACTH is produced in the pituitary, and also by lymphocytes and macrophages. In immunohistology this antibody stains corticotroph cells of the pituitary gland and benign and malignant tumours arising from these cells. | Details: Isotype: | IgG | Immunogen: | Synthetic human ACTH | Gene Symbol: POMC Entrez: | 5443 (Human) | Related Genes: | CRH, PRL, AVP, INS, C1QL1, GH1, GGH, AGT, PLOD1, REN, PBX1, MSX2, TRH, NLRP3, IFNAR1, SST, NPY, BRD2, PDYN, LEP, TAC1, VIP, GCG, CYP21A2, IL6, TNF, CCK, FOS, NR3C1, MC3R, MC2R, SERPINA6, IL2, GHRH, LCT, ALB, GRP, MC4R, PCSK1, LAMC2 | Background: ACTH occurs in cells of the anterior pituitary and in neurons in brain. It regulates the corticosteroid production in the adrenal cortex. Beta endorphin and Met enkephalin are endogenous opiates. MSH (melanocyte stimulating hormone) increases the pigmentation of skin by increasing melanin production in melanocytes. Species: Reactivity: | Reacts with Human. | Applications: Uses: | Immunohistochemistry-Paraffin, Immunohistochemistry-Frozen This product does not require protein digestion pre-treatment of paraffin sections. This product does not require antigen retrieval using heat treatment prior to staining of paraffin sections. | Dilutions: | Immunohistochemistry-Paraffin Immunohistochemistry-Frozen | Positive Controls: | 1 positive controls | Packaging: Buffer: | PBS, 1% Bovine Serum Albumin | Storage: | Store at 4C. Do not freeze. | Preservative: | 0.09% Sodium Azide | Limitations: | This product is for research use only and is not approved for use in humans or in clinical diagnosis. Products are guaranteed for 6 months from date of receipt, except for peptides and proteins which are guaranteed for 3 months. | |
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