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Description |
Unit |
Price
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납기 |
재고 |
DataSheet |
주문/견적 |
| LCA-23-310700 |
NB600-1172 |
AKT1 Antibody//Bovine, Human/Chicken |
1/EA |
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문의 |
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Subject
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AKT1 Antibody |
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Description
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/ Bovine, Human/Chicken |
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Clonality
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Poly |
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Company
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Novus biologicals |
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Application
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IHC-P, Western Blot |
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Conjugation
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Immunogen
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Contents
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Description:Summary: | Species: | Xp, Rt, Mu, Hu, Bv | | Applications: | WB, IHC | | Clonality: | Polyclonal | | | Gene: | AKT1 | | Purity: | Immunogen affinity purified | | Host: | Chicken | | | Specificity: | AKT | | Publications: | Antibody has not yet been mentioned in a publication. | Details: | Isotype: | IgY | | Immunogen: | Recombinant fragment: SDVAIVKEG WLHKRGEYIK TWRPRYFLLK NDGTFIGYKE RPQDVDQREA PLNNFSVAQC QLMKTERPRP NTFIIRCLQW TTVIERTFHV ETPEEREEWT TAIQTVADGL KKQEEEEMDF RSGSPSDNSG AEEMEVSLAK PKHRVTMNEF EYLKLLGKGT FGKVILVKEK ATGRYYAMKI LKKEVIVAKD EVAHTLTENR, corresponding to amino acids 2-200 of Human AKT. | | Localization: | Cytoplasmic and Nuclear | Gene Symbol: AKT1 | Entrez: | 207 (Human) | | | 11651 (Mouse) | | | 24185 (Rat) | | Related Genes: | PIK3CG, PTK2B, MAPK1, PIK3CA, PIK3CB, PIK3CD, MAPK3, EPHB2, INS, MTOR, EGFR, PTEN, CASP3, VEGFA, INSR, MAPK8, EGF, MAPK12, NFKB1, MAPK14, GRAP2, AHSA1, AIMP2, SLC2A4, CDC42, SRC, BCL2L1, BCL2, NOS3, RHO, RHOD, CDKN1A, IRS1, TNF, ERBB2, PSMC4, JUN, PTK2, FOXO1, IRS-1 | Background: The serine threonine protein kinase encoded by the AKT1 gene is catalytically inactive in serum starved primary and immortalized fibroblasts. AKT1 and the related AKT2 are activated by platelet derived growth factor. The activation is rapid and specific. In the developing nervous system AKT is a critical mediator of growth factor induced neuronal survival. Survival factors can suppress apoptosis in a transcription independent manner by activating the serine/threonine kinase AKT1, which then phosphorylates and inactivates components of the apoptotic machinery. Multiple alternatively spliced transcript variants have been found for this gene (referenced from entrez gene). Species: | Reactivity: | Cross-reacts with Human, Mouse, Rat, Xenopus laevis and Cow. Not yet tested in other species. | Applications: | Uses: | WB: Predicted molecular weight: 58 kDa. Optimal dilutions/concentrations should be determined by the end user. | | Dilutions: | immunohistochemistry 1/200, Western Blot 1/500 - 1/2000 | | Concentrations: | 1.0 mg/ml | Packaging: | Buffer: | PBS | | Storage: | Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles. | | Preservative: | No Preservative | | Limitations: | This product is for research use only and is not approved for use in humans or in clinical diagnosis. Products are guaranteed for 6 months from date of receipt, except for peptides and proteins which are guaranteed for 3 months. | |
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