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Description |
Unit |
Price
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납기 |
재고 |
DataSheet |
주문/견적 |
| LCA-23-310835 |
NB100-65713 |
Actin Alpha 2 Smooth Muscle Antibody (HHF35)//Canine, Chicken/Mouse |
1/EA |
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문의 |
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Subject
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Actin Alpha 2 Smooth Muscle Antibody (HHF35) |
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Description
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/ Canine, Chicken/Mouse |
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Clonality
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Mono |
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Company
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Novus biologicals |
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Application
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IHC-P, IHC-P |
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Conjugation
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Immunogen
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Contents
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Description:Summary: | Species: | Fe, Rb, Rt, Mk, Mu, Hu, Ch, Ca | | Applications: | IHC-Fr, IHC-P | | Clonality: | Monoclonal | | | Gene: | ACTA2 | | Purity: | Tissue culture supernatant | | Host: | Mouse | | | Specificity: | Recognizes muscle specific actin, a 42kD protein specific for actin present in skeletal, cardiac and smooth muscle. Clone HHF35 is specific for alpha actin and does not recognize beta actin. This may be useful in the study of tumors arising from these muscle cells, such as rhabdomyosarcomas, leiomyomas and leiomyosarcomas. | | Publications: | Antibody has not yet been mentioned in a publication. | Details: | Clone: | HHF35 | | Isotype: | IgG1 | | Immunogen: | Muscle actin, purified from human myocardium | Gene Symbol: ACTA2 | Entrez: | 59 (Human) | | | 11475 (Mouse) | | | 81633 (Rat) | | Related Genes: | MYH7, DES, ACTC1, NPPA, MYOD1, MYOG, MYH14, MYL1, NKX2-5, ACTA1, PLN, TTN, TGFBR1, GJA1, CDKN1A, TNNT2, HNRNPC, C2, PCNA, LMNA, MLC1, TGFBR2, HESX1, ELSPBP1, SGCD, HAND1, MSTN, GATA4, VCL, PSMD1, MYC, MYF5, MYF6, NOL3, VCAN, MYH11, FBN1, TGFB1, MSC, TNFRSF11A | Background: The two major cytoskeletal proteins implicated in cell motility are actin and myosin. Actin and myosin are constituents of many cell types and are involved in a myriad of cellular processes including locomotion, secretion, cytoplasmic streaming, phagocytosis and cytokinesis. Although actin is one of the most conserved eukaryotic proteins, it is expressed in mammals and birds as at least six isoforms characterized by electrophoresis and amino acid sequence analysis. Four of them represent the differentiation markers of muscle tissues and two are found in practically all cells. Species: | Reactivity: | Reacts with Mouse, Cat, Rabbit, Japanese macaque monkey, Dog, Rat, Chicken, Macaque monkey, Shrew and Human. | Applications: | Uses: | Immunohistochemistry-Paraffin, Immunohistochemistry-Frozen This product does not require protein digestion pre-treatment of paraffin sections.This product does not require antigen retrieval using heat treatment prior to staining of paraffin sections. | | Dilutions: | Immunohistochemistry-Paraffin 1:10 - 1:40, Immunohistochemistry-Frozen | Packaging: | Buffer: | PBS, 1% Bovine Serum Albumin | | Storage: | Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles. | | Preservative: | 0.09% Sodium Azide | | Limitations: | This product is for research use only and is not approved for use in humans or in clinical diagnosis. Products are guaranteed for 6 months from date of receipt, except for peptides and proteins which are guaranteed for 3 months. | |
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