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Cat. No |
Model |
Description |
Unit |
Price (VATº°µµ) |
³³±â |
Àç°í |
DataSheet |
ÁÖ¹®/°ßÀû |
LCA-23-310873 |
NB100-62170 |
Alpha 2 Macroglobulin Antibody//Human/Sheep |
1/EA |
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¹®ÀÇ |
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Subject
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Alpha 2 Macroglobulin Antibody |
Description
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/ Human/Sheep |
Clonality
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Poly |
Company
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Novus biologicals |
Application
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ID, IHC-P |
Conjugation
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Immunogen
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Contents
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Description:Summary: Species: | Hu | Applications: | ID, IHC-Fr | Clonality: | Polyclonal | | Gene: | A2M | Purity: | IgG purified | Host: | Sheep | | Specificity: | NB100-62170 recognises alpha 2-macroglobulin, a tetrameric glycoprotein of 720kD which functions as a proteinase inhibitor. | Details: Isotype: | IgG | Immunogen: | Human alpha 2 -macroglobulin purified from plasma | Localization: | Secreted | Gene Symbol: A2M Entrez: | 2 (Human) | Related Genes: | ALB, APOE, TF, SERPINC1, CP, PLG, HP, C3, LRP1, SERPINA3, SERPINA1, CRP, CSRP1, IL6, LYZ, TNF, MVP, C4A, ELANE, RPSA, PTPRA, SERPINF2, PSEN1, C2orf3, PSEN2, IL5, ACE, TERF1, KLK3, CTSG, PROC, PLAU, C1D, PROS1, AFP, VWF, APP, PLAG1, PSAT1, NPEPPS | Background: Alpha 2 macroglobulin is a serum protein which is mainly synthesised in the liver. It functions as a broad range irreversible proteinase inhibitor that forms a "trap" around most proteases. Alpha 2 macroglobulin is a tetrameric molecule, and with a molecular weight of 720 kDa, it so large a molecule that it tends to remain intravascular. Following conformational change the proteinase is deposited within a central cavity where it is still active but prevented from further contact with its substrate. Removal of the complex is mediated by the generation of recognition sites which react with receptors on a variety of cells including macrophages and liver cells. Alpha 2 macroglobulin is localized on the surface of peripheral blood lymphocytes. Species: Reactivity: | Reacts with: Bovine, Horse, Guinea Pig, Pig, Dog, Cat, Rabbit | Applications: Uses: | This antibody is useful for Immunohistochemistry-Frozen & Immunodiffusion | Dilutions: | Immunohistochemistry-Frozen Immunodiffusion | Positive Controls: | 1 positive controls | Packaging: Buffer: | Glycine buffered saline pH7.4 | Storage: | Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles. | Preservative: | 0.09% Sodium Azide | Limitations: | This product is for research use only and is not approved for use in humans or in clinical diagnosis. Products are guaranteed for 6 months from date of receipt, except for peptides and proteins which are guaranteed for 3 months. | |
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