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| Cat. No |
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Description |
Unit |
Price
(VAT별도) |
납기 |
재고 |
DataSheet |
주문/견적 |
| LCA-23-310881 |
NB300-343 |
Alpha 2 Macroglobulin Antibody//Human, Mouse,/Chicken |
1/EA |
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문의 |
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Subject
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Alpha 2 Macroglobulin Antibody |
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Description
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/ Human, Mouse,/Chicken |
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Clonality
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Poly |
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Company
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Novus biologicals |
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Application
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ELISA, Western Blot |
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Conjugation
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Immunogen
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Contents
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Description:Summary: | Species: | Rt, Mu, Hu | | Applications: | WB, ELISA | | Clonality: | Polyclonal | | | Gene: | A2M | | Purity: | Immunogen affinity purified | | Host: | Chicken | | | Specificity: | alpha 2 Macroglobulin | | Publications: | Antibody has not yet been mentioned in a publication. | Details: | Isotype: | IgY | | Immunogen: | Full length protein (Human). | Gene Symbol: A2M | Entrez: | 2 (Human) | | | 232345 (Mouse) | | | 24153 (Rat) | | Related Genes: | ALB, APOE, TF, SERPINC1, CP, PLG, HP, C3, LRP1, SERPINA3, SERPINA1, CRP, CSRP1, IL6, LYZ, TNF, MVP, C4A, ELANE, RPSA, PTPRA, SERPINF2, PSEN1, C2orf3, PSEN2, IL5, ACE, TERF1, KLK3, CTSG, PROC, PLAU, C1D, PROS1, AFP, VWF, APP, PLAG1, PSAT1, NPEPPS | Background: Alpha 2 macroglobulin is a serum protein which is mainly synthesised in the liver. It functions as a broad range irreversible proteinase inhibitor that forms a "trap" around most proteases. Alpha 2 macroglobulin is a tetrameric molecule, and with a molecular weight of 720 kDa, it so large a molecule that it tends to remain intravascular. Following conformational change the proteinase is deposited within a central cavity where it is still active but prevented from further contact with its substrate. Removal of the complex is mediated by the generation of recognition sites which react with receptors on a variety of cells including macrophages and liver cells. Alpha 2 macroglobulin is localized on the surface of peripheral blood lymphocytes. Species: | Reactivity: | Cross-reacts with Human, Mouse and Rat. Not yet tested in other species. | Applications: | Uses: | WB: Predicted molecular weight: 163 kDa. Optimal dilutions/concentrations should be determined by the end user. | | Dilutions: | ELISA 5mg/ml, Western Blot | | Concentrations: | 1.0 mg/ml | | Positive Controls: | 1 positive controls | Packaging: | Buffer: | PBS | | Storage: | Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles. | | Preservative: | 0.02% Sodium Azide | | Limitations: | This product is for research use only and is not approved for use in humans or in clinical diagnosis. Products are guaranteed for 6 months from date of receipt, except for peptides and proteins which are guaranteed for 3 months. | |
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