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Cat. No |
Model |
Description |
Unit |
Price (VATº°µµ) |
³³±â |
Àç°í |
DataSheet |
ÁÖ¹®/°ßÀû |
LCA-23-310909 |
NB120-14224 |
Alpha 1 Fetoprotein Antibody//Human/Chicken |
1/EA |
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¹®ÀÇ |
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Subject
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Alpha 1 Fetoprotein Antibody |
Description
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/ Human/Chicken |
Clonality
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Poly |
Company
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Novus biologicals |
Application
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ICC, IHC-P, Western Blot |
Conjugation
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Immunogen
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Contents
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Description:Summary: Species: | Hu | Applications: | WB, IHC, ICC | Clonality: | Polyclonal | | Gene: | AFP | Purity: | IgG purified | Host: | Chicken | | Specificity: | alpha 1 Fetoprotein | Publications: | Antibody has not yet been mentioned in a publication. | Details: Isotype: | IgY | Immunogen: | Synthetic peptide: LWAARYDKII PSCCKAENAV ECFQTKAATV TKELRESSLL NQHACAVMKN FGTRTFQAIT VTKLSQKFTK VNFTEIQKLV LDVAHVHEHC CRGDVLDCLQ DGEKIMSYIC SQQDTLSNKI TECCKLTTLE RGQCIIHAEN DEKPEGLSPN LNRFLGDRDF NQFSSGEKNI FLASFVHEYS RRHPQLAVSV ILRVAKGYQE LLEKCFQTEN PLECQDKGEE ELQKYIQESQ ALAKRSCGLF , corresponding to amino acids 180-420 of Human alpha 1 Fetoprotein. | Localization: | Secreted | Gene Symbol: AFP Entrez: | 174 (Human) | Related Genes: | TRIM26, ALB, FAM126A, PSG2, CEACAM5, CEACAM7, CGA, CGB5, ACHE, TF, HGF, ALPP, TP53, KRT19, VIM, GGT1, IL6, EGF, ADAM17, PTPRC, KLK3, CSH1, PAPPA, CSH2, ACE, IL2, SLC17A5, SERPINA1, SOS1, MUC16, PSAT1, PCNA, PROS1, PLAG1, NPEPPS, CLTA, GUCY2D, INS, REG3A, GGT2 | Background: Alpha 1 Fetoprotein is a major plasma protein produced by the yolk sac and the liver during fetal life. Alpha fetoprotein expression in adults is often associated with hepatoma or teratoma. However, hereditary persistance of alpha-fetoprotein may also be found in individuals with no obvious pathology. The protein is thought to be the fetal counterpart of serum albumin, and the alpha fetoprotein and albumin genes are present in tandem in the same transcriptional orientation on chromosome 4. Alpha fetoprotein is found in monomeric as well as dimeric and trimeric forms, and binds copper, nickel, fatty acids and bilirubin. The level of alpha fetoprotein in amniotic fluid is used to measure renal loss of protein to screen for spina bifida and anencephaly. Expression has been documented in human adrenal, liver, ovary, testis, and pancreas. ESTs have been isolated from normal human brain, liver/spleen, embryo and uterus tissue libraries. Species: Reactivity: | Cross-reacts with Human.Expected to cross-react with Chimpanzee (100% identity with immunogen) and Gorilla (100% identity with immunogen) due to sequence homology.Not yet tested in other species. | Applications: Uses: | ICC: Use at a dilution of 1/200. IHC: Use at a dilution of 1/200. Western Blot: Use at a dilution of 1/500. Detects a band of approximately 75 kDa (predicted molecular weight: 69 kDa). Optimal dilutions/concentrations should be determined by the end user. | Dilutions: | Immunocytochemistry, immunohistochemistry, Western Blot, | Concentrations: | 1.0 mg/ml | Positive Controls: | 1 positive controls | Packaging: Buffer: | PBS | Storage: | Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles. | Preservative: | No Preservative | Limitations: | This product is for research use only and is not approved for use in humans or in clinical diagnosis. Products are guaranteed for 6 months from date of receipt, except for peptides and proteins which are guaranteed for 3 months. | |
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