|
| |
| Cat. No |
Model |
Description |
Unit |
Price
(VAT별도) |
납기 |
재고 |
DataSheet |
주문/견적 |
| LCA-23-311106 |
NB600-895 |
Apc1 [phospho Ser377] Antibody//Bovine, Canine/Rabbit |
1/EA |
|
|
|
|
문의 |
|
|
|
|
|
|
|
Subject
|
Apc1 [phospho Ser377] Antibody |
|
Description
|
/ Bovine, Canine/Rabbit |
|
Clonality
|
Poly |
|
Company
|
Novus biologicals |
|
Application
|
ELISA, IHC-P, IHC-P, Western Blot |
|
Conjugation
|
|
|
Immunogen
|
|
|
Contents
|
Description:Summary: | Species: | Mu, Ca, Bv, Rt, Hu | | Applications: | IHC-P, WB, IHC, ELISA | | Clonality: | Polyclonal | | | Gene: | ANAPC1 | | Purity: | Immunogen affinity purified | | Host: | Rabbit | | | Specificity: | Specific for human APC1 phosphorylated at S377. Minimal reactivity is expected with the non-phosphorylated form of the protein. | | Publications: | Antibody has not yet been mentioned in a publication. | Details: | Modification: | phospho Ser377 | | Isotype: | IgG | | Immunogen: | Synthetic peptide: C-SHNQSpPKRHS, corresponding to amino acids 373-382 of Human Apc1. | | Localization: | Secreted | Gene Symbol: ANAPC1 | Entrez: | 64682 (Human) | | | 17222 (Mouse) | | | 311412 (Rat) | | Related Genes: | APC, PROC, ANAPC2, APOC2, SLC25A23, APC2, CDC27, CDC16, CDC23, RNF123, ANAPC10, CDC20, WNT1, CDH1, PCSK1, PLK1, CTNNB1, FZR1, ANKS1B, MAPRE2, ANAPC11, CDK2AP1, BUB1, ESR1, MAPRE1, COX7A2L, PARK2, SCARA3, ANAPC7, MUL1, SLC25A25, TPR, TRIM50, PKA, MAD2L1, MTPN, CCNA2, CCND2, C10orf46, ANAPC4 | Background: APC1 is 1 of at least 11 subunits of the anaphase promoting complex (APC), which functions at the metaphase to anaphase transition of the cell cycle and is regulated by spindle checkpoint proteins. The APC is an E3 ubiquitin ligase that targets cell cycle regulatory proteins for degradation by the proteasome, thereby allowing progression through the cell cycle. Species: | Reactivity: | Cross-reacts with Human. Expected to cross-react with Rat, Cow and Dog (all show 100% identity with immunogen) due to sequence homology. Also expected to cross-react with Mouse (90% identity with immunogen). | Applications: | Uses: | This antibody is useful for ELISA, Western Blot and Immunohistochemistry. In Western Blot, detects a band of approximately 215 kDa (predicted molecular weight: 215 kDa). | | Dilutions: | ELISA 1:2000 - 1:10000, immunohistochemistry 5.0 Ug/ml, Western Blot 1:200 - 1:1000, Immunohistochemistry-Paraffin | | Concentrations: | 1.13 mg/ml | Packaging: | Buffer: | 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2 | | Storage: | Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles. | | Preservative: | 0.01% Sodium Azide | | Limitations: | This product is for research use only and is not approved for use in humans or in clinical diagnosis. Products are guaranteed for 6 months from date of receipt, except for peptides and proteins which are guaranteed for 3 months. | |
|
|
|
|
