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| Cat. No |
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Description |
Unit |
Price
(VAT별도) |
납기 |
재고 |
DataSheet |
주문/견적 |
| LCA-23-311180 |
NB120-19880 |
A RAF Antibody//Human, Mouse,/Rabbit |
1/EA |
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문의 |
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Subject
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A RAF Antibody |
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Description
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/ Human, Mouse,/Rabbit |
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Clonality
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Poly |
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Company
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Novus biologicals |
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Application
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Western Blot |
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Conjugation
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Immunogen
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Contents
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Description:Summary: | Species: | Rt, Mu, Hu | | Applications: | WB | | Clonality: | Polyclonal | | | Gene: | ARAF | | Purity: | protein A purified | | Host: | Rabbit | | Details: | Isotype: | IgG | | Immunogen: | Synthetic peptide (Human) (C terminal). | | Localization: | Cytoplasmic | Gene Symbol: ARAF | Entrez: | 369 (Human) | | | 11836 (Mouse) | | | 64363 (Rat) | | Related Genes: | RAF1, ZHX2, BRAF, NDUFAB1, SNRPE, FASN, OXSM, MAPK1, EPHB2, FAS, MAP2K1, PIK3CG, LYST, MAPK3, TIMP1, SHBG, ABP1, MCAT, EGF, GALP, AKT1, SRC, GLYAT, SYN1, CAT, TH1L, C3orf39, CFP, CYP19A1, PKC, MAP3K1, FOS, PIK3CA, PIK3CB, PIK3CD, A4GALT, HSP90AA1, RRAS2, KCNH8, CDKN1A | Background: The RAF family of signaling proteins has three isoforms: A RAF, RAF 1 and B RAF. These proteins are instrumental in forwarding the stimulus generated by mitogens from monomeric G proteins to the MAP kinase pathway. RAF 1 is known to be downstream of Ras and binds to it by an N terminal noncatalytic domain. This domain is conserved in A RAF and B RAF. 14-3-3 is also known to be an activator of RAFs. Activated RAF directly phosphorylates and activates MEK. A RAF is expressed at a very high concentration in urogenital and kidney tissues. Species: | Reactivity: | Cross-reacts with Human, Mouse and Rat. | Applications: | Uses: | Western Blot Predicted molecular weight 69 kDa. | | Dilutions: | Western Blot 5 ug/mg of protein lysate | | Concentrations: | 0.5 mg/ml | Packaging: | Buffer: | BSA, 10mM PBS. pH 7.4 | | Storage: | Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles. | | Preservative: | Sodium Azide | | Limitations: | This product is for research use only and is not approved for use in humans or in clinical diagnosis. Products are guaranteed for 6 months from date of receipt, except for peptides and proteins which are guaranteed for 3 months. | |
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