|
|
Cat. No |
Model |
Description |
Unit |
Price (VATº°µµ) |
³³±â |
Àç°í |
DataSheet |
ÁÖ¹®/°ßÀû |
LCA-23-315812 |
NLS2675 |
F4/80 Antibody//Human/Rabbit |
1/EA |
|
|
|
|
¹®ÀÇ |
|
|
|
|
|
|
Subject
|
F4/80 Antibody |
Description
|
/ Human/Rabbit |
Clonality
|
Poly |
Company
|
Novus biologicals |
Application
|
IHC-P, IHC-P |
Conjugation
|
|
Immunogen
|
|
Contents
|
Description:Summary: Species: | Hu | Applications: | IHC-P, IHC | Clonality: | Polyclonal | | Gene: | EMR1 | Purity: | Immunogen affinity purified | Host: | Rabbit | | Specificity: | EGF-Like Module-Containing Mucin-Like Receptor 1 | Details: Immunogen: | N-terminal extracellular domain of human | Gene Symbol: EMR1 Entrez: | 2015 (Human) | Related Genes: | Cd97, Egf, Egf, Emr1, EGF, Cd97, CD97, Emr4, Cd55, CD55, Cd55, EMR2, Tnf, Cd68, Emr4p, Cd68, Eltd1, INS, EMR4P, Tnf, CD68, Ccl2, Ccl2, IL6, CCL2, Il6, Il6, TNF, EMR3, GPR151, Sct, Ccl3, PPARG, IL1B, Nos2, Fcgr3, MRGPRX1, IL8, FCGR3B, FCGR3A | Background: EGF-Like Module Containing Mucin-Like Hormone Receptor-Like Sequence 1 (EMR1) is characterized as an Orphan-B GPCR with an unknown ligand. The C-terminus contains seven hydrophobic segments, characteristic of a G protein-coupled receptor. The N-terminus of EMR1 has 6 EGF-like modules, separated from the transmembrane segments by a serine/threonine-rich domain, a feature reminiscent of mucin-like, single-span, integral membrane glycoproteins with adhesive properties. F4/80 is a monoclonal antibody that recognizes a murine macrophage- restricted cell surface glycoprotein whose amino acid sequence has been determined to be the EMR1 gene. Therefore, the data from this antibody can be used to derive gene expression of mouse EMR1. EMR1 has been reported to be expressed in human peripheral blood mononuclear cells, monocytes, and hematopoietic and solid tumor-derived cell lines. ESTs have been isolated from human normal spleen and mixed liver/spleen libraries and from human kidney, colon, brain, and bone marrow cancer libraries. Species: Applications: Uses: | Immunohistochemistry of Formalin fixed paraffin embedded sections. | Dilutions: | immunohistochemistry , Immunohistochemistry-Paraffin | Concentrations: | 1.0 mg/ml | Packaging: Buffer: | Phosphate buffered saline, pH 7.7 | Storage: | Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles. | Preservative: | 0.01% Sodium Azide | Limitations: | This product is for research use only and is not approved for use in humans or in clinical diagnosis. Products are guaranteed for 6 months from date of receipt, except for peptides and proteins which are guaranteed for 3 months. | |
|
|
|
|