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| Cat. No |
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Description |
Unit |
Price
(VAT별도) |
납기 |
재고 |
DataSheet |
주문/견적 |
| LCA-23-315171 |
NB100-1424 |
ACTR1B Antibody//Human/Goat |
1/EA |
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문의 |
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Subject
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ACTR1B Antibody |
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Description
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/ Human/Goat |
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Clonality
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Poly |
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Company
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Novus biologicals |
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Application
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ELISA, IHC-P, Western Blot |
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Conjugation
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Immunogen
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Contents
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Description:Summary: | Species: | Hu | | Applications: | WB, IHC, ELISA | | Clonality: | Polyclonal | | | Gene: | ACTR1B | | Purity: | Immunogen affinity purified | | Host: | Goat | | | Specificity: | This may crossreact with ACTR1A. | | Publications: | Antibody has not yet been mentioned in a publication. | Details: | Isotype: | IgG | | Immunogen: | Synthetic peptide: YEEDGSRAIHRKT representing the C terminus of the human protein (residues 363-375),according to NP_005726. | | Localization: | Cytoplasmic | Gene Symbol: ACTR1B | Entrez: | 10120 (Human) | | Swiss Prot: | NP_005726. (Human) | | Related Genes: | PCSK2, PCSK1, CBX4, PKD2, KRT17, KRT6B, ENPP1, CDKN1A, INS, AKT1, EGF, TP53, CASP3, EGFR, AR, FURIN, BCL2, BTG2, PIK3CG, KLK3, MAPK1, MMP9, TCEAL1, D4S234E, TNFSF10, IFRD1, PLAU, SUB1, PCSK4, VEGFA, PSAT1, PROS1, PLAG1, NPEPPS, FOLH1, PARP1, BAX, BCL2L1, CCND1, MAPK8 | Background: In addition to conventional actins, there are several actin-related proteins. The ACTR1B protein and the ACTR1A protein are of equal length, and they share 90% amino acid identity and 96% amino acid similarity. ACTR1B is expressed in the cytosol as part of the dynactin complex. The dynactin complex has been shown to localize to multiple structures within the cell, including membrane organelles, the centrosome, spindle poles, and spindle pole microtubules during mitosis and prometaphase kinetochores. It regulates dyneinmediated vesicle movement on microtubules as well as spindle assembly and cell division. ACTR1B appears to be ivolved in dynein-driven vesicle movement. Species: | Reactivity: | Human, mouse and rat. | Applications: | Uses: | This antibody is useful for Peptide ELISA, Immunohistochemistry and Western Blot. Approx 45kDa band observed in human heart and brain lysates (predicted MW of 43kDa according to NP_005726). | | Dilutions: | ELISA 1:128000, immunohistochemistry 3-5ug/ml, Western Blot 0.5-2ug/ml | | Concentrations: | 0.5 mg/ml | | Positive Controls: | 2 positive controls | Packaging: | Buffer: | Tris-saline containing 0.02% Na azide (pH7.3) with 0.5% BSA | | Storage: | Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles. | | Preservative: | 0.02% Sodium Azide | | Limitations: | This product is for research use only and is not approved for use in humans or in clinical diagnosis. Products are guaranteed for 6 months from date of receipt, except for peptides and proteins which are guaranteed for 3 months. | |
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