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Cat. No |
Model |
Description |
Unit |
Price (VATº°µµ) |
³³±â |
Àç°í |
DataSheet |
ÁÖ¹®/°ßÀû |
LCA-23-316067 |
NB100-77699 |
F4/80 Antibody (BM8)//Mouse/Rat |
1/EA |
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Subject
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F4/80 Antibody (BM8) |
Description
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/ Mouse/Rat |
Clonality
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Mono |
Company
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Novus biologicals |
Application
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FACS, IHC-P, Western Blot |
Conjugation
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Immunogen
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Contents
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Description:Summary: Species: | Mu | Applications: | IHC-Fr, WB, FACS | Clonality: | Monoclonal | | Gene: | EMR1 | Purity: | Immunogen affinity purified | Host: | Rat | | Specificity: | F4/80 (BM8) | Publications: | Antibody has been mentioned in at least 1 publication. | Details: Clone: | BM8 | Isotype: | IgG2a Kappa | Gene Symbol: EMR1 Entrez: | 2015 (Human) | | 13733 (Mouse) | Related Genes: | Cd97, Egf, Egf, Emr1, EGF, Cd97, CD97, Emr4, Cd55, CD55, Cd55, EMR2, Tnf, Cd68, Emr4p, Cd68, Eltd1, INS, EMR4P, Tnf, CD68, Ccl2, Ccl2, IL6, CCL2, Il6, Il6, TNF, EMR3, GPR151, Sct, Ccl3, PPARG, IL1B, Nos2, Fcgr3, MRGPRX1, IL8, FCGR3B, FCGR3A | Background: F4/80 is a 160 kD glycoprotein. It is characterized as a member of the epidermal growth factor (EGF)-transmembrane 7 (TM7) family. F4/80, also known as EMR1 or Ly71, has been widely used as a murine macrophage marker, which is expressed on majority of tissue macrophages including peritoneal macrophages, macrophages in lung, gut, thymus and red pulp of spleen (but not on the macrophages located in T cell areas of the spleen, lymph node and Peyer's patch), Kuffer cells, Langerhans cells, bone marrow stromal cells. F4/80 has also been shown on a subset of dendritic cells. The biological ligand of F4/80 has not been identified, but it has been reported that F4/80 is required for induction of CD8 T cells-mediated peripheral tolerance. Species: Applications: Uses: | Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For immunofluorescent staining, the suggested use of this reagent is: 1.0 microgram per one million cells in 100 microliter. Immunohistochemistry-frozen sections. It is recommended that the reagent be titrated for optimal performance for each application. | Dilutions: | flow cytometry / FACS analysis , Western Blot , Immunohistochemistry-Frozen | Packaging: Buffer: | Phosphate-buffered solution, pH 7.2 | Storage: | Store at 4C. Do not freeze. | Preservative: | 0.09% Sodium Azide | Limitations: | This product is for research use only and is not approved for use in humans or in clinical diagnosis. Products are guaranteed for 6 months from date of receipt, except for peptides and proteins which are guaranteed for 3 months. | |
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