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Description |
Unit |
Price
(VAT별도) |
납기 |
재고 |
DataSheet |
주문/견적 |
| LCA-49-237579 |
RB-1638-PABX |
Anti-NF kappa B / p65 (Rel A) Ab-1 Polyclonal Antibody, Unconjugated/1.0ml/Human, Mouse, Rat, Hamster, Rabbit, Cow, Pig, Dog, Drossophila, Xenopus/Request Info |
1/EA |
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문의 |
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Subject
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Anti-NF kappa B / p65 (Rel A) Ab-1 Polyclonal Antibody, Unconjugated |
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Description
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1.0ml / Human, Mouse, Rat, Hamster, Rabbit, Cow, Pig, Dog, Drossophila, Xenopus/Request Info |
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Clonality
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Poly |
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Company
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Lab Vision |
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Application
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Request Info |
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Conjugation
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Unconjugated |
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Immunogen
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NF kappa B / p65 (Rel A) |
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Contents
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NF kappa B is a heterodimer consisting of a 50kDa DNA binding subunit and a 65kDa transactivating subunit (RelA). The p50/p65 heterodime is present in the cytoplasm in inactive form bound to its inhibitor, I?B. Upon stimulation of cells with stimuli like LPS, Interleukin-1, IkB gets phosphorylated and degraded by proteosomes releasing the activated NFkB which goes to the nucleus inducing gene expression. NFkB was originally identified as transcriptional activator for kappa light cahain gene in B cells.
Species Reactivity: Human, Mouse, Rat, Hamster, Rabbit, Cow, Pig, Dog, Drossophila, Xenopus. Others-not tested.
Comments:
Ab-1 recognizes RelA. |
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