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| Cat. No |
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Description |
Unit |
Price
(VAT별도) |
납기 |
재고 |
DataSheet |
주문/견적 |
| LCA-23-311403 |
NB100-87027 |
B Raf Antibody//Human/Rabbit |
1/EA |
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문의 |
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Subject
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B Raf Antibody |
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Description
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/ Human/Rabbit |
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Clonality
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Poly |
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Company
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Novus biologicals |
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Application
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IP, Western Blot |
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Conjugation
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Immunogen
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Contents
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Description:Summary: | Species: | Hu | | Applications: | IP, WB | | Clonality: | Polyclonal | | | Gene: | BRAF | | Purity: | Immunogen affinity purified | | Host: | Rabbit | | Details: | Immunogen: | The epitope recognized by this antibody maps to a region between residue 25 and 75 of human v-raf murine sarcoma viral oncogene homolog B1 using the numbering given in entry NP_004324.2 (GeneID 673). | Gene Symbol: BRAF | Entrez: | 673 (Human) | | Swiss Prot: | NP_004324.2 (Human) | | Related Genes: | RAF1, MAPK1, ZHX2, EPHB2, KRAS, CDKN2A, HRAS, MAPK3, TP53, EGFR, NRAS, MAP2K1, MLH1, SNRPE, PIK3CG, PIK3CA, AKT1, RET, MAP2K2, PTEN, CTNNB1, MAPK12, ARAF, RAP1A, CDKN1A, MSH2, TERF2IP, APC, EGF, CCND1, ERBB2, PROC, CDK4, PIK3CB, PIK3CD, RASSF1, MGMT, TCEAL1, D4S234E, PKA | Background: This gene encodes a protein belonging to the raf/mil family of serine/threonine protein kinases. This protein plays a role in regulating the MAP kinase/ERKs signaling pathway, which affects cell division, differentiation, and secretion. Mutations in this gene are associated with cardiofaciocutaneous syndrome, a disease characterized by heart defects, mental retardation and a distinctive facial appearance. Mutations in this gene have also been associated with various cancers, including non-Hodgkin lymphoma, colorectal cancer, malignant melanoma, thyroid carcinoma, non-small cell lung carcinoma, and adenocarcinoma of lung. A pseudogene, which is located on chromosome X, has been identified for this gene. [provided by RefSeq] Species: Applications: | Uses: | This antibody is useful for western blot and immunoprecipitation. | | Dilutions: | Western Blot 1:2000-1:10000,immunoprecipitation 2-5 mcg/mg lysate | | Concentrations: | 0.2 mg/ml | | Positive Controls: | 1 positive controls | Packaging: | Buffer: | Tris-buffered Saline containing 0.1% BSA | | Storage: | Store at 4C. Do not freeze. | | Preservative: | 0.09% Sodium Azide | | Limitations: | This product is for research use only and is not approved for use in humans or in clinical diagnosis. Products are guaranteed for 6 months from date of receipt, except for peptides and proteins which are guaranteed for 3 months. | |
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