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Description |
Unit |
Price
(VAT별도) |
납기 |
재고 |
DataSheet |
주문/견적 |
| LCA-23-310216 |
H00000018-D01P |
ABAT Antibody//Human/Rabbit |
1/EA |
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문의 |
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Subject
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ABAT Antibody |
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Description
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/ Human/Rabbit |
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Clonality
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Poly |
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Company
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Novus biologicals |
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Application
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ELISA, Western Blot |
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Conjugation
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Immunogen
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Contents
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Description:Summary: | Protein Type: | Full length Protein | | Species: | Hu | | Applications: | WB, ELISA | | Clonality: | Polyclonal | | | Gene: | ABAT | | Purity: | protein A purified | | Host: | Rabbit | | | Specificity: | Reacts with 4-aminobutyrate aminotransferase. | Details: | Immunogen: | ABAT (NP_000654.2, 1 a.a. ~ 500 a.a) full-length human protein. | | Epitope: | MASMLLAQRLACSFQHSYRLLVPGSR HISQAAAKVDVEFDYDGPLMKTEVPG PRSQELMKQLNIIQNAEAVHFFCNYE ESRGNYLVDVDGNRMLDLYSQISSVP IGYSHPALLKLIQQPQNASMFVNRPA LGILPPENFVEKLRQSLLSVAPKGMS QLITMACGSCSNENALKTIFMWYRSK ERGQRGFSQEELETCMINQAPGCPDY SILSFMGAFHGRTMGCLATTHSKAIH KIDIPSFDWPIAPFPRLKYPL | Gene Symbol: ABAT | Entrez: | 18 (Human) | | Swiss Prot: | NP_000654.2 (Human) | | Related Genes: | GABA-T, GAD1, ALDH5A1, ACHE, PDXP, PLP1, PRDX5, PTHLH, PRSS33, IKZF4, PRL, CAT, CHAT, POMC, GLYAT, TH, GLS, GLUL, GLUD1, H6PD, UGDH, TRH, GAD2, CA1, OAT, LAMC2, SLC6A1, COMT, KCNH2, ERG, INS, PDXK, MAO-B, GAT-1, GFAP, ME1, PLOD1, CSAD, QRSL1, ME3 | Background: 4-aminobutyrate aminotransferase (ABAT) is responsible for catabolism of gamma-aminobutyric acid (GABA), an important, mostly inhibitory neurotransmitter in the central nervous system, into succinic semialdehyde. The active enzyme is a homodimer of 50-kD subunits complexed to pyridoxal-5-phosphate. The protein sequence is over 95% similar to the pig protein. GABA is estimated to be present in nearly one-third of human synapses. ABAT in liver and brain is controlled by 2 codominant alleles with a frequency in a Caucasian population of 0.56 and 0.44. The ABAT deficiency phenotype includes psychomotor retardation, hypotonia, hyperreflexia, lethargy, refractory seizures, and EEG abnormalities. Multiple alternatively spliced transcript variants encoding the same protein isoform have been found for this gene. [provided by RefSeq] Species: Applications: | Uses: | This antibody is reactive against transfected lysate in western blot, and as a detection antibody in ELISA. | | Dilutions: | ELISA,Western Blot | Notes: Genbank Accession: NM_000663.3 This product is produced by and distributed for Abnova, a company based in Taiwan. Packaging: | Buffer: | 1x PBS, pH 7.2 | | Storage: | Store at -20C. Avoid freeze-thaw cycles. | | Preservative: | No Preservative | | Limitations: | This product is for research use only and is not approved for use in humans or in clinical diagnosis. Products are guaranteed for 6 months from date of receipt, except for peptides and proteins which are guaranteed for 3 months. | |
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