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Cat. No |
Model |
Description |
Unit |
Price (VATº°µµ) |
³³±â |
Àç°í |
DataSheet |
ÁÖ¹®/°ßÀû |
LCA-23-310222 |
NBP1-21385 |
AAK1 Antibody//Human/Rabbit |
1/EA |
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¹®ÀÇ |
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Subject
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AAK1 Antibody |
Description
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/ Human/Rabbit |
Clonality
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Poly |
Company
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Novus biologicals |
Application
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IP, Western Blot |
Conjugation
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Immunogen
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Contents
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Description:Summary: Species: | Hu | Applications: | IP, WB | Clonality: | Polyclonal | | Gene: | AAK1 | Purity: | Immunogen affinity purified | Host: | Rabbit | | Details: Isotype: | IgG | Immunogen: | The epitope recognized by this antibody maps to a region between residue 310 and 360 of human AP2 associated kinase 1 using the numbering given in entry AAI11966.1 (GeneID 22848). | Gene Symbol: AAK1 Entrez: | 22848 (Human) | Swiss Prot: | AAI11966.1 (Human) | Related Genes: | TF, GAK, TFAP2A, GTF3A, FABP4, ACTR2, AURKA, AP2M1, EGF, JUN, AP1M2, RNF111, AURKB, NUMB, ANGPTL2, SCYL2, CTSD, FOS, FOSB, NLRP2, SYNJ1, AICDA, JUND, JUNB, TFRC, MAP6, ERBB3, AMPH, EEA1, EPS15, EPS15L1, LRP1, PPA1, HSPA8, PKN1, SRC, RAB5A, RABGEF1, TSSK2, SCD5 | Background: AAK1 (AP2-associated kinase 1) is a Ser/Thr protein kinase. The rat homolog was first identified in a screen of a rat brain cDNA library using a domain of the alpha subunit of the heterotetrameric AP2 complex as bait. The AP2 complex is one of two major coat proteins of endocytic vesicles that function in receptor-mediated endocytosis and the recycling of synaptic vesicles. AAK1 is responsible for phosphorylating the mu subunit of AP2 to promote clathrin-mediated endocytosis. Species: Applications: Uses: | This antibody is useful for western blot and immunoprecipitation. | Dilutions: | Western Blot 1:2000 to 1:10000, Immunoprecipitation 2 to 5 mcg/mg lysate, | Concentrations: | 0.2 mg/ml | Packaging: Buffer: | Tris-buffered Saline containing 0.1% BSA | Storage: | Store at 4C. Do not freeze. | Preservative: | 0.09% Sodium Azide | Limitations: | This product is for research use only and is not approved for use in humans or in clinical diagnosis. Products are guaranteed for 6 months from date of receipt, except for peptides and proteins which are guaranteed for 3 months. | |
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