|
| |
| Cat. No |
Model |
Description |
Unit |
Price
(VAT별도) |
납기 |
재고 |
DataSheet |
주문/견적 |
| LCA-23-310281 |
NB110-58748Sample Size AvailableHa, Hu, MuWB(1)$295.005 Lipo |
5 Lipoxygenase Antibody//Human, Rat/Polyclonal |
1/EA |
|
|
|
|
문의 |
|
|
|
|
|
|
|
Subject
|
5 Lipoxygenase Antibody |
|
Description
|
/ Human, Rat/Polyclonal |
|
Clonality
|
Mono |
|
Company
|
Novus biologicals |
|
Application
|
PEP-ELISA, Western Blot |
|
Conjugation
|
|
|
Immunogen
|
|
|
Contents
|
Description:Summary: | Protein Type: | Full length Protein | | Species: | Hu | | Applications: | WB, ELISA | | Clonality: | Polyclonal | | | Gene: | ALOX5 | | Purity: | protein A purified | | Host: | Rabbit | | | Specificity: | Reacts with arachidonate 5-lipoxygenase. | Details: | Immunogen: | ALOX5 (NP_000689.1, 1 a.a. ~ 674 a.a) full-length human protein. | | Epitope: | MPSYTVTVATGSQWFAGTDDYIYLSL VGSAGCSEKHLLDKPFYNDFERGAVD SYDVTVDEELGEIQLVRIEKRKYWLN DDWYLKYITLKTPHGDYIEFPCYRWI TGDVEVVLRDGRAKLARDDQIHILKQ HRRKELETRQKQYRWMEWNPGFPLSI DAKCHKDLPRDIQFDSEKGVDFVLNY SKAMENLFINRFMHMFQSSWNDFADF EKIFVKISNTISERVMNHWQEDLMFG YQFLNGCNPVLIRRCTELPEK | Gene Symbol: ALOX5 | Entrez: | 240 (Human) | | Swiss Prot: | NP_000689.1 (Human) | | Related Genes: | CD19, PTGS2, ALOX5AP, ALOX12, C4A, ALOX15, LTB, LTA4H, LOX, YWHAZ, TNF, APP, PTGS1, SGCG, ATP6V0A4, PLP2, COX8A, COX5A, GSTP1, MPO, PLEKHM1, MAPK1, PLA2G6, ARHGDIB, LTB4R, PLA2G2A, CYSLTR1, CYSLTR2, PLA2G4A, PLA2G1B, 5LO, LTA, 12-LO, KIAA0101, KAT5, MAPK3, PTGDS, UBE4B, IL4, UBE4A | Background: This gene encodes a member of the lipoxygenase gene family and plays a dual role in the synthesis of leukotrienes from arachidonic acid. The encoded protein, which is expressed specifically in bone marrow-derived cells, catalyzes the conversion of arachidonic acid to 5(S)-hydroperoxy-6-trans-8,11,14-cis-eicosatetraenoic acid, and further to the allylic epoxide 5(S)-trans-7,9-trans-11,14-cis-eicosatetrenoic acid (leukotriene A4). Leukotrienes are important mediators of a number of inflammatory and allergic conditions. Mutations in the promoter region of this gene lead to a diminished response to antileukotriene drugs used in the treatment of asthma and may also be associated with atherosclerosis and several cancers. Alternatively spliced transcript variants have been observed, but their full-length nature has not been determined. [provided by RefSeq] Species: Applications: | Uses: | This antibody is reactive against tissue and transfected lysate in western blot, and as a detection antibody in ELISA. | | Dilutions: | ELISA,Western Blot | Notes: Genbank Accession: NM_000698.2 This product is produced by and distributed for Abnova, a company based in Taiwan. Packaging: | Buffer: | 1x PBS, pH 7.2 | | Storage: | Store at -20C. Avoid freeze-thaw cycles. | | Preservative: | No Preservative | | Limitations: | This product is for research use only and is not approved for use in humans or in clinical diagnosis. Products are guaranteed for 6 months from date of receipt, except for peptides and proteins which are guaranteed for 3 months. | |
|
|
|
|
