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Price
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납기 |
재고 |
DataSheet |
주문/견적 |
| LCA-23-310279 |
NB110-58749Sample Size AvailableBv, Hu, Mu, Rb, RtWB(1)$295. |
5 Lipoxygenase Antibody//Human, Mouse/Polyclonal |
1/EA |
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문의 |
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Subject
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5 Lipoxygenase Antibody |
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Description
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/ Human, Mouse/Polyclonal |
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Clonality
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Mono |
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Company
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Novus biologicals |
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Application
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ELISA, IHC-P, Western Blot |
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Conjugation
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Immunogen
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Contents
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Description:Summary: | Protein Type: | Full length Protein | | Species: | Hu | | Applications: | ELISA, WB | | Clonality: | Polyclonal | | | Gene: | ALOX5 | | Purity: | Whole antisera | | Host: | Mouse | | | Specificity: | ALOX5 - arachidonate 5-lipoxygenase, | Details: | Immunogen: | ALOX5 (1 a.a. ~ 674 a.a) full-length human protein. | | Epitope: | MPSYTVTVATGSQWFAGTDDYIYLSL VGSAGCSEKHLLDKPFYNDFERGAVD SYDVTVDEELGEIQLVRIEKRKYWLN DDWYLKYITLKTPHGDYIEFPCYRWI TGDVEVVLRDGRAKLARDDQIHILKQ HRRKELETRQKQYRWMEWNPGFPLSI DAKCHKDLPRDIQFDSEKGVDFVLNY SKAMENLFINRFMHMFQSSWNDFADF EKIFVKISNTISERVMNHWQEDLMFG YQFLNGCNPVLIRRCTELPEK | Gene Symbol: ALOX5 | Entrez: | 240 (Human) | | Swiss Prot: | NP_000689.1 (Human) | | Related Genes: | CD19, PTGS2, ALOX5AP, ALOX12, C4A, ALOX15, LTB, LTA4H, LOX, YWHAZ, TNF, APP, PTGS1, SGCG, ATP6V0A4, PLP2, COX8A, COX5A, GSTP1, MPO, PLEKHM1, MAPK1, PLA2G6, ARHGDIB, LTB4R, PLA2G2A, CYSLTR1, CYSLTR2, PLA2G4A, PLA2G1B, 5LO, LTA, 12-LO, KIAA0101, KAT5, MAPK3, PTGDS, UBE4B, IL4, UBE4A | Background: This gene encodes a member of the lipoxygenase gene family and plays a dual role in the synthesis of leukotrienes from arachidonic acid. The encoded protein, which is expressed specifically in bone marrow-derived cells, catalyzes the conversion of arachidonic acid to 5(S)-hydroperoxy-6-trans-8,11,14-cis-eicosatetraenoic acid, and further to the allylic epoxide 5(S)-trans-7,9-trans-11,14-cis-eicosatetrenoic acid (leukotriene A4). Leukotrienes are important mediators of a number of inflammatory and allergic conditions. Mutations in the promoter region of this gene lead to a diminished response to antileukotriene drugs used in the treatment of asthma and may also be associated with atherosclerosis and several cancers. Alternatively spliced transcript variants have been observed, but their full-length nature has not been determined. Species: | Reactivity: | Human. Other species not tested. | Applications: | Uses: | Antibody reactive against Recombinant Protein with GST tag on ELISA and Western Blot and also on transfected lysate in western blot. GST tag alone is used as a negative control. | | Dilutions: | Western Blot 1:500,ELISA | Notes: This product is produced by and distributed for Abnova, a company based in Taiwan. Packaging: | Buffer: | This antibody is in antisera and the concentration is unavailable. | | Storage: | Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles. | | Preservative: | No Preservative | | Limitations: | This product is for research use only and is not approved for use in humans or in clinical diagnosis. Products are guaranteed for 6 months from date of receipt, except for peptides and proteins which are guaranteed for 3 months. | |
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