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Subject
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68kDa Neurofilament Light Antibody (7D1) |
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Description
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/ Bovine, Hamster/Mouse |
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Clonality
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Mono |
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Company
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Novus biologicals |
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Application
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IF, Western Blot |
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Conjugation
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Immunogen
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Contents
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Description:Summary: | Species: | Rt, Po, Mu, Ha, Bv | | Applications: | WB, IF | | Clonality: | Monoclonal | | | Gene: | NEFL | | Purity: | Ascites | | Host: | Mouse | | | Specificity: | Neurofilament NF-L (7D1) | | Publications: | Antibody has not yet been mentioned in a publication. | Details: Gene Symbol: NEFL | | 18039 (Mouse) | | | 83613 (Rat) | | Related Genes: | NEFM, NF-H, NFASC, GFAP, MPZ, VIM, SOD1, KIF1B, LAMC2, MAPT, PRPH, NEFH, PMP22, MAP2, GJB1, MAD2L1BP, MBP, IGFALS, NF200, METAP2, HSPB1, ENO2, GAP-43, MFN2, PXMP2, NES, GCLC, GCA, GMCL1, GMCL1L, MTMR2, SYP, NGF, PHLDA2, BDNF, GARS, CDK5, DLG3, DES, MBL2 | Background: Neurofilaments are the 10nm or intermediate filament proteins found specifically in neurons, and are composed predominantly of three major proteins called NF-L, NF-M and NF-H. NF-L is the neurofilament light or low molecular weight polypeptide and runs on SDS-PAGE gels at about 68kDa. Antibodies to NF-L are useful for identifying neuronal cells and their processes in tissue sections and in tissue culture. NF-L antibody can also be useful in the diagnostics of neurofilament accumulations seen in many neurological diseases, such as Lou Gehrig's disease and Alzheimer's disease. Mutations in the protein coding region of the human NF-L gene cause some forms of Charcot-Marie-Tooth disease (1). Species: | Reactivity: | human, cow, pig, mouse and rat | Applications: | Uses: | Immunofluorescence and Western Blot | | Dilutions: | immunofluorescence 1:100-1:500, Western Blot 1:5000 - 1:10000 | Packaging: | Storage: | Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles. | | Preservative: | No Preservative | | Limitations: | This product is for research use only and is not approved for use in humans or in clinical diagnosis. Products are guaranteed for 6 months from date of receipt, except for peptides and proteins which are guaranteed for 3 months. | |
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