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Description |
Unit |
Price
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납기 |
재고 |
DataSheet |
주문/견적 |
| LCA-23-310244 |
NBP1-19627 |
5HT4 Receptor Antibody//Human, Mouse,/Rabbit |
1/EA |
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문의 |
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Subject
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5HT4 Receptor Antibody |
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Description
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/ Human, Mouse,/Rabbit |
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Clonality
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Poly |
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Company
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Novus biologicals |
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Application
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IF, IHC-P, Western Blot |
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Conjugation
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Immunogen
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Contents
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Description:Summary: | Species: | Rt, Mu, Hu | | Applications: | IF, IHC, WB | | Clonality: | Polyclonal | | | Gene: | HTR4 | | Purity: | Affinity purified | | Host: | Rabbit | | | Specificity: | SR-4 (D47) detects endogenous levels of SR-4 protein. | Details: Gene Symbol: HTR4 | Entrez: | 3360 (Human) | | | 15562 (Mouse) | | | 25324 (Rat) | | Related Genes: | 5-HT3, HTR2A, HTR1A, HTR7, TNFRSF11A, HTR1B, ADCY7, HTR2C, HTR6, HTR2B, CA1, POMC, TAC1, HTR1D, HTF, VIP, HTR1F, HTR5A, SLC6A4, DIO2, HTR1E, BBS9, BDNF, EFS, CALR, CALCA, CCK, TRH, PKA, LMOD1, S100A12, HTR3A, GPR151, MRGPRX1, LGR6, OXER1, VN1R17P, FZD4, MRGPRX3, MRGPRX4 | Background: Serotonin (also designated 5-hydroxytryptamine or 5-HT) is a molecule that functions as a neurotransmitter, a hormone and a mitogen, and it is predominantly expressed in the gut, platelets and central nervous system (CNS). In the CNS, serotonin modulates several processes, including anxiety, sleep, appetite, behavior and drug abuse. In platelets and gut, serotonin plays a major role in cardiovascular function and motility of the gastrointestinal tract, respectively. Serotonin mediates its effects through several of G protein coupled receptors, designated 5-HT receptors or alternatively SR receptors. SR-3 is a ligand-gated ion channel, whereas all other known serotonin receptor subtypes are G protein-coupled receptors. The gene which encodes SR-3 maps to human chromosome 11q23.1-q23.2. SR-4 mediates widespread effects in central and peripheral nervous systems. The gene which encodes SR-4 maps to human chromosome 5q31-q33. SR-7 belongs to the superfamily of G protein-coupled receptors. The gene which encodes SR-7 maps to human chromosome 10q21-q24. Species: | Reactivity: | Human, Mouse, Rat | Applications: | Uses: | This antibody is useful for Western Blot, Immunohistochemistry and Immunofluorescence.Western blot analysis of SR-4 (D47) antibody in extracts from 293 cells treated with insulin 0.01U.Immunohistochemistry analyzes of SR-4 (D47) antibody in paraffin-embedded human brain tissue. | | Dilutions: | Western Blot 1:500-1:1000,immunohistochemistry 1:50-1:200,immunofluorescence 1:50-1:200, | Packaging: | Buffer: | Phosphate buffered saline (PBS) with 15 mM sodium azide, approx. pH 7.2. | | Storage: | Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles. | | Preservative: | No Preservative | | Limitations: | This product is for research use only and is not approved for use in humans or in clinical diagnosis. Products are guaranteed for 6 months from date of receipt, except for peptides and proteins which are guaranteed for 3 months. | |
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