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Description |
Unit |
Price
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납기 |
재고 |
DataSheet |
주문/견적 |
| LCA-23-310273 |
NB110-58749G |
5 Lipoxygenase Antibody [DyLight 488]//Bovine, Human/Rabbit |
1/EA |
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문의 |
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Subject
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5 Lipoxygenase Antibody [DyLight 488] |
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Description
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/ Bovine, Human/Rabbit |
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Clonality
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Poly |
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Company
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Novus biologicals |
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Application
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Western Blot |
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Conjugation
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Immunogen
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Contents
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Description:Summary: | Species: | Bv, Rt, Mu, Hu, Rb | | Applications: | WB | | Clonality: | Polyclonal | | | Gene: | ALOX5 | | Purity: | Immunogen affinity purified | | Host: | Rabbit | | Details: | Conjugate: | DyLight 488 | | Immunogen: | A synthetic peptide made to a C-terminal region within residues 600-674 of the human protein. [Swiss-Prot# P09917] | | Localization: | Cytoplasmic | Gene Symbol: ALOX5 | Entrez: | 240 (Human) | | Swiss Prot: | P09917 (Human) | | Related Genes: | CD19, PTGS2, ALOX5AP, ALOX12, C4A, ALOX15, LTB, LTA4H, LOX, YWHAZ, TNF, APP, PTGS1, SGCG, ATP6V0A4, PLP2, COX8A, COX5A, GSTP1, MPO, PLEKHM1, MAPK1, PLA2G6, ARHGDIB, LTB4R, PLA2G2A, CYSLTR1, CYSLTR2, PLA2G4A, PLA2G1B, 5LO, LTA, 12-LO, KIAA0101, KAT5, MAPK3, PTGDS, UBE4B, IL4, UBE4A | Background: This gene encodes a protein which, with Arachidonate 5-lipoxygenase-activating protein, is required for leukotriene synthesis. Leukotrienes are arachidonic acid metabolites which have been implicated in various types of inflammatory responses, including asthma, arthritis and psoriasis. This protein localizes to the plasma membrane. Inhibitors of its function impede translocation of 5-lipoxygenase from the cytoplasm to the cell membrane and inhibit 5-lipoxygenase activation. Species: | Reactivity: | Reacts with human, rabbit, mouse, rat and bovine. | Applications: | Uses: | This antibody is useful in Western Blot, where a band is seen at ~80 kDa. There may be some non-specific bands at non-interfering lower molecular weights. | | Dilutions: | Western Blot 1:500-1:1000 | | Concentrations: | 1.0 mg/ml | | Conjugated Ab's: | 4 conjugated antibodies | Packaging: | Buffer: | 50mM sodium borate | | Storage: | Store at 4C. Do not freeze. | | Preservative: | No Preservative | | Limitations: | This product is for research use only and is not approved for use in humans or in clinical diagnosis. Products are guaranteed for 6 months from date of receipt, except for peptides and proteins which are guaranteed for 3 months. | |
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