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Description |
Unit |
Price
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납기 |
재고 |
DataSheet |
주문/견적 |
| LCA-23-310291 |
NB100-65477 |
200kDa Neurofilament Heavy Antibody (2-E30)//Mammal, Rat/Mouse |
1/EA |
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Subject
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200kDa Neurofilament Heavy Antibody (2-E30) |
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Description
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/ Mammal, Rat/Mouse |
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Clonality
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Mono |
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Company
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Novus biologicals |
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Application
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IHC-P, Western Blot |
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Conjugation
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Immunogen
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Contents
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Description:Summary: | Species: | Rt, Ma | | Applications: | IHC-Fr, WB | | Clonality: | Monoclonal | | | Gene: | NEFH | | Purity: | Tissue culture supernatant | | Host: | Mouse | | | Specificity: | 3H11 reacts with an epitope dependent on the last 84 amino acids of rat NF-M (145 kD). Neurofilament proteins consist of the light NF-L, medium NF-M and heavy NF-H subunits.Most neurons appear to express these proteins but their ratios and phosphorylation states are variable. | | Publications: | Antibody has not yet been mentioned in a publication. | Details: | Clone: | 2-E30 | | Isotype: | IgG | | Immunogen: | Recombinant fusion protein RM:677-845 containing the last 169 amino acids of rat neurofilament (145 kD). Purified from E. coli inclusion bodies by Ion exchange chromatography. Corresponds to the rat NF-M KE segment (lysine glutamate) (ref.1) | Gene Symbol: NEFH | | 24588 (Rat) | | Related Genes: | NEFM, NEFL, NFASC, SOD1, PRPH, GFAP, LDLR, FH, CFH, MAP2, MAPT, IGFALS, NES, REN, PRNP, AGT, MBP, UCHL1, METAP2, ACHE, HOXA9, MT1M, MAPK1, VIM, CLDN6, IL6, PSEN1, GPR158, PSEN2, RSPO4, PKP1, CDK5, ATP2A2, GAP-43, RANGAP1, MAPK9, CA3, SLC17A5, TAC1, LIF | Background: Neurofilaments usually contain three intermediate filament proteins: L, M, and H which are involved in the maintenance of neuronal caliber. The extra mass and high charge density that distinguish the neurofilament proteins from all other intermediate filament proteins are due to the tailpiece extensions. This region may form a charged scaffolding structure suitable for interaction with other neuronal components or ions. Species: | Reactivity: | Reacts with Bird, Mammal and Rat. | Applications: | Uses: | Immunohistochemistry-Frozen, Western Blot | | Dilutions: | Western Blot , Immunohistochemistry-Frozen 1:50 - 1:1000 | Packaging: | Storage: | Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles. | | Preservative: | 0.09% Sodium Azide | | Limitations: | This product is for research use only and is not approved for use in humans or in clinical diagnosis. Products are guaranteed for 6 months from date of receipt, except for peptides and proteins which are guaranteed for 3 months. | |
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