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Description |
Unit |
Price
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납기 |
재고 |
DataSheet |
주문/견적 |
| LCA-23-310292 |
H00004744-M01 |
200kDa Neurofilament Heavy Antibody (2E8)//Human/Mouse |
1/EA |
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Subject
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200kDa Neurofilament Heavy Antibody (2E8) |
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Description
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/ Human/Mouse |
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Clonality
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Mono |
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Company
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Novus biologicals |
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Application
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ELISA, Western Blot |
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Conjugation
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Immunogen
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Contents
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Description:Summary: | Species: | Hu | | Applications: | WB, ELISA | | Clonality: | Monoclonal | | | Gene: | NEFH | | Purity: | IgG purified | | Host: | Mouse | | Details: | Clone: | 2E8 | | Isotype: | IgG2a Kappa | | Immunogen: | NEFH (NP_066554, 263 a.a. ~ 364 a.a) partial recombinant protein with GST tag. | | Epitope: | LKCDVTSALREIRAQLEGHAVQSTLQ SEEWFRVRLDRLSEAAKVNTDAMRSA QEEITEYRRQLQARTTELEALKSTKD SLERQRSELEDRHQADIASYQEA* | Gene Symbol: NEFH | Entrez: | 4744 (Human) | | Omim: | 105400, 162230, (Human) | | Swiss Prot: | NP_066554 (Human) | | Related Genes: | NEFM, NEFL, NFASC, SOD1, PRPH, GFAP, LDLR, FH, CFH, MAP2, MAPT, IGFALS, NES, REN, PRNP, AGT, MBP, UCHL1, METAP2, ACHE, HOXA9, MT1M, MAPK1, VIM, CLDN6, IL6, PSEN1, GPR158, PSEN2, RSPO4, PKP1, CDK5, ATP2A2, GAP-43, RANGAP1, MAPK9, CA3, SLC17A5, TAC1, LIF | Background: Neurofilaments are type IV intermediate filament heteropolymers composed of light, medium, and heavy chains. Neurofilaments comprise the axoskeleton and functionally maintain neuronal caliber. They may also play a role in intracellular transport to axons and dendrites. This gene encodes the heavy neurofilament protein. This protein is commonly used as a biomarker of neuronal damage and susceptibility to amyotrophic lateral sclerosis (ALS) has been associated with mutations in this gene. [provided by RefSeq] Species: | Reactivity: | Human. Other species not tested. | Applications: | Uses: | Antibody reactive against cell lysate and recombinant protein for western blot. It has also been used for ELISA. | | Dilutions: | ELISA,Western Blot 1:500 | Notes: This product is produced by and distributed for Abnova, a company based in Taiwan. Packaging: | Buffer: | In 1x PBS, pH 7.2 | | Storage: | Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles. | | Preservative: | No Preservative | | Limitations: | This product is for research use only and is not approved for use in humans or in clinical diagnosis. Products are guaranteed for 6 months from date of receipt, except for peptides and proteins which are guaranteed for 3 months. | |
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