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Description |
Unit |
Price
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납기 |
재고 |
DataSheet |
주문/견적 |
| LCA-23-310300 |
H00004744-A01 |
200kDa Neurofilament Heavy Antibody//Human/Mouse |
1/EA |
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Subject
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200kDa Neurofilament Heavy Antibody |
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Description
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/ Human/Mouse |
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Clonality
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Poly |
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Company
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Novus biologicals |
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Application
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ELISA, Western Blot |
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Conjugation
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Immunogen
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Contents
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Description:Summary: | Species: | Hu | | Applications: | WB, ELISA | | Clonality: | Polyclonal | | | Gene: | NEFH | | Purity: | Whole antisera | | Host: | Mouse | | | Specificity: | NEFH - neurofilament, heavy polypeptide 200kDa | Details: | Immunogen: | NEFH (NP_066554, 263 a.a. ~ 364 a.a) partial recombinant protein with GST tag. | | Epitope: | LKCDVTSALREIRAQLEGHAVQSTLQ SEEWFRVRLDRLSEAAKVNTDAMRSA QEEITEYRRQLQARTTELEALKSTKD SLERQRSELEDRHQADIASYQEA* | Gene Symbol: NEFH | Entrez: | 4744 (Human) | | Omim: | 105400|162230 (Human) | | Swiss Prot: | NP_066554 (Human) | | Related Genes: | NEFM, NEFL, NFASC, SOD1, PRPH, GFAP, LDLR, FH, CFH, MAP2, MAPT, IGFALS, NES, REN, PRNP, AGT, MBP, UCHL1, METAP2, ACHE, HOXA9, MT1M, MAPK1, VIM, CLDN6, IL6, PSEN1, GPR158, PSEN2, RSPO4, PKP1, CDK5, ATP2A2, GAP-43, RANGAP1, MAPK9, CA3, SLC17A5, TAC1, LIF | Background: Neurofilaments are type IV intermediate filament heteropolymers composed of light, medium, and heavy chains. Neurofilaments comprise the axoskeleton and functionally maintain neuronal caliber. They may also play a role in intracellular transport to axons and dendrites. This gene encodes the heavy neurofilament protein. This protein is commonly used as a biomarker of neuronal damage and susceptibility to amyotrophic lateral sclerosis (ALS) has been associated with mutations in this gene. [provided by RefSeq] Species: | Reactivity: | Human. Other species not tested. | Applications: | Uses: | The quality control of this antibody is limited to Western blot on the immunizing protein. It has also been used for ELISA. Abnova's recommended working dilutions for western analysis are as follows:1:500 dilution for ascites1:1000 for purified Ig1:500-1:1000 for polysera | | Dilutions: | ELISA,Western Blot 1:500 | Notes: This product is produced by and distributed for Abnova, a company based in Taiwan. Packaging: | Buffer: | This antibody is in antisera and the concentration is unavailable. | | Storage: | Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles. | | Preservative: | No Preservative | | Limitations: | This product is for research use only and is not approved for use in humans or in clinical diagnosis. Products are guaranteed for 6 months from date of receipt, except for peptides and proteins which are guaranteed for 3 months. | |
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