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Description |
Unit |
Price
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납기 |
재고 |
DataSheet |
주문/견적 |
| LCA-23-310302 |
NBP1-05209 |
200kDa Neurofilament Heavy Antibody//Rat/Mouse |
1/EA |
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문의 |
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Subject
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200kDa Neurofilament Heavy Antibody |
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Description
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/ Rat/Mouse |
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Clonality
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Mono |
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Company
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Novus biologicals |
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Application
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IF, Western Blot |
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Conjugation
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Immunogen
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Contents
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Description:Summary: | Species: | Rt | | Applications: | WB, IF | | Clonality: | Monoclonal | | | Gene: | NEFH | | Purity: | Ascites | | Host: | Mouse | | | Specificity: | Neurofilament NF-H | | Publications: | Antibody has not yet been mentioned in a publication. | Details: Gene Symbol: NEFH | | 24587 (Rat) | | Related Genes: | NEFM, NEFL, NFASC, SOD1, PRPH, GFAP, LDLR, FH, CFH, MAP2, MAPT, IGFALS, NES, REN, PRNP, AGT, MBP, UCHL1, METAP2, ACHE, HOXA9, MT1M, MAPK1, VIM, CLDN6, IL6, PSEN1, GPR158, PSEN2, RSPO4, PKP1, CDK5, ATP2A2, GAP-43, RANGAP1, MAPK9, CA3, SLC17A5, TAC1, LIF | Background: Neurofilaments are the 10nm or intermediate filament proteins found specifically in neurons, and are composed predominantly of three major proteins called NF-L, NF-M and NF-H. NF-H is the neurofilament high or heavy molecular weight polypeptide and runs on SDS-PAGE gels at 200-220 kDa, with some variability across species boundaries. Antibodies to NF-H are useful for identifying neuronal cells and their processes in tissue sections and in tissue culture. NF-H antibodies can also be useful in the diagnostics of neurofilament accumulations seen in many neurological diseases, such as Amyotrophic Lateral Sclerosis (also known as Lou Gehrig's disease) and Alzheimer's disease. NBP1-05209 is one of numerous antibodies which reacts preferentially with the axonal phosphorylated forms of NF-H. Interestingly these phosphorylated forms of NF-H are normally restricted to axons, while less phosphorylated forms are found in dendrites. However in numerous damage and disease states, phosphorylated NF-H can be detected with NBP1-05209 in dendritic and perikaryal neurofilaments. Species: Applications: | Uses: | Immunofluorescence and Western Blot | | Dilutions: | immunofluorescence 1:1000, Western Blot 1:10000 | Packaging: | Storage: | Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles. | | Preservative: | No Preservative | | Limitations: | This product is for research use only and is not approved for use in humans or in clinical diagnosis. Products are guaranteed for 6 months from date of receipt, except for peptides and proteins which are guaranteed for 3 months. | |
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