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Description |
Unit |
Price
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납기 |
재고 |
DataSheet |
주문/견적 |
| LCA-23-310308 |
NBP1-28832 |
160kDa Neurofilament Medium Antibody (3H11)//Chicken, Human/Mouse |
1/EA |
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문의 |
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Subject
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160kDa Neurofilament Medium Antibody (3H11) |
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Description
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/ Chicken, Human/Mouse |
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Clonality
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Mono |
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Company
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Novus biologicals |
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Application
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IF, Western Blot |
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Conjugation
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Immunogen
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Contents
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Description:Summary: | Species: | Ch, Mu, Hu, Rt | | Applications: | WB, IF | | Clonality: | Monoclonal | | | Gene: | NEFM | | Purity: | Tissue culture supernatant | | Host: | Mouse | | | Specificity: | NBP1-28832 recognizes the carboxy terminus of neurofilament M (NF-M), one of three neurofilament proteins (NF-H, NF-M and NF-L). Neurofilaments are 10nm or intermediate filaments found specifically in neurons, with especially high concentrations along the axons, where they appear to control axonal diameter. It is thought that phosphorylation of NF-M results in the formation of interfilament cross-bridges that are important in the maintenance of axonal calibre. | Details: | Clone: | 3H11 | | Isotype: | IgG1 | | Immunogen: | Recombinant fusion protein containing the extreme C-terminus of rat NF-M expressed in and purified from E.coli. | Gene Symbol: NEFM | Entrez: | 4741 (Human) | | | 24588 (Rat) | | Swiss Prot: | P12839 (Human) | | Related Genes: | NEFL, NF-H, NFASC, GFAP, VIM, NEFH, PRPH, MAPT, MAP2, CDK5, SOD1, NES, MAPK1, METAP2, MAPK3, IGFALS, ENO2, MBP, NGF, EGF, MAP1B, SYP, GAP-43, MAP-2, BDNF, KIAA0101, CDK5R1, GLYAT, CAT, ENO1, PKA, EPHB2, MYB, DES, CHAT, FGF2, PRG2, FOS, NTRK1, JUN | Background: This antibody recognises the carboxy terminus of neurofilament M (NF-M), one of three neurofilament proteins (NF-H, NF-M and NF-L). Neurofilaments are 10nm or intermediate filaments found specifically in neurons, with especially high concentrations along the axons, where they appear to control axonal diameter. It is thought that phosphorylation of NF-M results in the formation of interfilament cross-bridges that are important in the maintenance of axonal calibre. Species: | Reactivity: | Rat. Expected to cross react with Human, Mouse, Chicken. | Applications: | Uses: | This antibody is useful for Immunofluorescence and Western Blot. | | Dilutions: | immunofluorescence,Western Blot, | Packaging: | Storage: | Store at 4C short term. Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles. | | Preservative: | 0.065% Sodium Azide | | Limitations: | This product is for research use only and is not approved for use in humans or in clinical diagnosis. Products are guaranteed for 6 months from date of receipt, except for peptides and proteins which are guaranteed for 3 months. | |
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