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Description |
Unit |
Price
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납기 |
재고 |
DataSheet |
주문/견적 |
| LCA-23-310312 |
NB110-93491 |
160kDa Neurofilament Medium Antibody//Chicken, Human/Mouse |
1/EA |
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문의 |
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Subject
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160kDa Neurofilament Medium Antibody |
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Description
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/ Chicken, Human/Mouse |
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Clonality
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Mono |
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Company
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Novus biologicals |
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Application
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IF, Western Blot |
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Conjugation
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Immunogen
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Contents
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Description:Summary: | Species: | Rt, Mu, Hu, Ch | | Applications: | WB, IF | | Clonality: | Monoclonal | | | Gene: | NEFM | | Purity: | Tissue culture supernatant | | Host: | Mouse | | | Specificity: | Specific for the 145k Neurofilament M protein. | | Publications: | Antibody has not yet been mentioned in a publication. | Details: | Isotype: | IgG | | Immunogen: | Recombinant fusion protein containing the extreme C-terminus of rat NF-M expressed in and purified from E. coli. | Gene Symbol: NEFM | Entrez: | 4741 (Human) | | | 18040 (Mouse) | | | 24588 (Rat) | | Related Genes: | NEFL, NF-H, NFASC, GFAP, VIM, NEFH, PRPH, MAPT, MAP2, CDK5, SOD1, NES, MAPK1, METAP2, MAPK3, IGFALS, ENO2, MBP, NGF, EGF, MAP1B, SYP, GAP-43, MAP-2, BDNF, KIAA0101, CDK5R1, GLYAT, CAT, ENO1, PKA, EPHB2, MYB, DES, CHAT, FGF2, PRG2, FOS, NTRK1, JUN | Background: Neurofilaments are the 10nm or intermediate filament proteins found specifically in neurons, and are composed predominantly of three major proteins called NF-L, NF-M and NF-H (1). NF-M is the neurofilament middle or medium molecular weight polypeptide and runs on SDS-PAGE gels at 145-160 kDa, with some variability across species boundaries. Antibodies to NF-M are useful for identifying neuronal cells and their processes in tissue sections and in tissue culture. NF-M antibodies can also be useful to visualize neurofilament accumulations seen in many neurological diseases, such as Amyotrophic Lateral Sclerosis (Lou Gehrig's disease) and Alzheimer's disease (2). Species: | Reactivity: | The antibody has been directly tested for reactivity in chicken, human, mouse and rat tissues. | Applications: | Uses: | Immunofluorescence and Western Blot | | Dilutions: | immunofluorescence 1:100, Western Blot 1:1,000 | | Positive Controls: | 1 positive controls | Packaging: | Storage: | Store at -20C. Avoid freeze-thaw cycles. | | Preservative: | 10mM Sodium Azide | | Limitations: | This product is for research use only and is not approved for use in humans or in clinical diagnosis. Products are guaranteed for 6 months from date of receipt, except for peptides and proteins which are guaranteed for 3 months. | |
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