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Description |
Unit |
Price
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납기 |
재고 |
DataSheet |
주문/견적 |
| LCA-23-310331 |
NBP1-19694 |
14-3-3 gamma Antibody//Human, Mouse,/Rabbit |
1/EA |
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문의 |
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Subject
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14-3-3 gamma Antibody |
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Description
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/ Human, Mouse,/Rabbit |
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Clonality
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Poly |
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Company
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Novus biologicals |
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Application
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IF, IHC-P, Western Blot |
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Conjugation
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Immunogen
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Contents
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Description:Summary: | Species: | Rt, Mu, Hu | | Applications: | IF, IHC, WB | | Clonality: | Polyclonal | | | Gene: | YWHAG | | Purity: | Affinity purified | | Host: | Rabbit | | | Specificity: | 14-3-3 gamma (M81) detects endogenous levels of 14-3-3 gamma protein. | Details: Gene Symbol: YWHAG | Entrez: | 7532 (Human) | | Related Genes: | TH, YWHAQ, YWHAZ, MAPK1, CDC25C, CHEK1, SFN, RAF1, YWHAE, LAMC2, PIK3CG, CDC2, PPA1, SNAP25, TSC1, PIK3CA, PIK3CB, PIK3CD, PKC, AVP, KPNA6, CHEK2, IL3, PTGER2, GTF2I, ZHX2, MDM4, POLD1, CDKN1C, APBB1, BAX, JUN, TP53, GTF2IRD1, PRNP, ELN, HSPB6, MAPK3, TSC2, ZYX | Background: 14-3-3 proteins regulate many cellular processes relevant to cancer biology, notably apoptosis, mitogenic signaling and cell-cycle checkpoints. Seven isoforms comprise this family of signaling intermediates, denoted 14-3-3 beta, gamma, episilon, zeta, eta, theta and sigma. 14-3-3 proteins form dimers that present two binding sites for ligand proteins, thereby bringing together two proteins that may not otherwise associate. These ligands largely share a 14-3-3 consensus binding motif and exhibit serine/threonine phosphorylation. 14-3-3 proteins function in broad regulation of these ligand proteins, by cytoplasmic sequestration, occupation of interaction domains and import/export sequences, prevention of degradation, activation/repression of enzymatic activity and facilitation of protein modification, and thus loss of expression contributes to a vast array of pathogenic cellular activities. Species: | Reactivity: | Human, Mouse, Rat | Applications: | Uses: | This antibody is useful for Western Blot, Immunohistochemistry and Immunofluorescence.Western blot analysis of 14-3-3 gamma (M81) antibody in extracts from K562 cells treated with insulin 0.01U.Immunohistochemistry analyzes of 14-3-3 gamma (M81) antibody in paraffin-embedded human brain tissue. | | Dilutions: | Western Blot 1:500-1:1000,immunohistochemistry 1:50-1:200,immunofluorescence 1:50-1:200, | Packaging: | Buffer: | Phosphate buffered saline (PBS) with 15 mM sodium azide, approx. pH 7.2. | | Storage: | Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles. | | Preservative: | No Preservative | | Limitations: | This product is for research use only and is not approved for use in humans or in clinical diagnosis. Products are guaranteed for 6 months from date of receipt, except for peptides and proteins which are guaranteed for 3 months. | |
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