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| Cat. No |
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Description |
Unit |
Price
(VAT별도) |
납기 |
재고 |
DataSheet |
주문/견적 |
| LCA-23-310333 |
NBP1-22960 |
14-3-3 epsilon Antibody (5A5)//Human/Mouse |
1/EA |
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문의 |
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Subject
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14-3-3 epsilon Antibody (5A5) |
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Description
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/ Human/Mouse |
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Clonality
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Mono |
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Company
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Novus biologicals |
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Application
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ELISA, Western Blot |
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Conjugation
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Immunogen
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Contents
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Description:Summary: | Species: | Hu | | Applications: | WB, ELISA | | Clonality: | Monoclonal | | | Gene: | YWHAE | | Purity: | protein G purified | | Host: | Mouse | | | Specificity: | Anti-human 14-3-3 epsilon mAb, clone 5A5, is derived from hybridization of mouse FO myeloma cells with spleen cells from BALB/c mice immunized with a recombinant human 14-3-3 epsilon protein. | | Publications: | Antibody has not yet been mentioned in a publication. | Details: | Clone: | 5A5 | | Isotype: | IgG2a Kappa | | Immunogen: | Recombinant human 14-3-3 epsilon (1-255aa) purified from E. coli | Gene Symbol: YWHAE | Entrez: | 7531 (Human) | | Related Genes: | EPO, FANCB, BCR, CSF3, CD34, RARS, TP53, TNF, EPX, RUNX1, TIMP1, KITLG, CDKN2B, THPO, MLL, IL3, LMLN, MPO, ANPEP, PAFAH1B1, CD33, INVS, HRAS, NRAS, CDKN2A, KIT, FAS, IL6, CD4, SUB1, VEGFA, MPL, MECOM, TH, CASP3, MVD, JAK2, FASLG, IL2, FLT3 | Background: This protein belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals, and this protein is 100% identical to the mouse ortholog. 14-3-3 proteins are localized in neurons, and are axonally transported to the nerve terminals. They may be also present, at lower levels, in various other eukaryotic tissues. It interacts with CDC25 phosphatases, RAF1 and IRS1 proteins, suggesting its role in diverse biochemical activities related to signal transduction, such as cell division and regulation of insulin sensitivity. It has also been implicated in the pathogenesis of small cell lung cancer. Species: Applications: | Uses: | The antibody has been tested by ELISA and Western blot analysis. | | Dilutions: | ELISA , Western Blot 1:1000-1:3000 | | Concentrations: | 1.0 mg/ml | Packaging: | Buffer: | Liquid. In Phosphate-Buffered Saline (pH 7.4) | | Storage: | Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles. | | Preservative: | 0.1% Sodium Azide | | Limitations: | This product is for research use only and is not approved for use in humans or in clinical diagnosis. Products are guaranteed for 6 months from date of receipt, except for peptides and proteins which are guaranteed for 3 months. | |
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