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| Cat. No |
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Description |
Unit |
Price
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납기 |
재고 |
DataSheet |
주문/견적 |
| LCA-23-310334 |
NBP1-04358 |
14-3-3 Beta Antibody (J2E9)//Human/Mouse |
1/EA |
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문의 |
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Subject
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14-3-3 Beta Antibody (J2E9) |
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Description
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/ Human/Mouse |
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Clonality
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Mono |
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Company
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Novus biologicals |
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Application
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ELISA, Western Blot |
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Conjugation
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Immunogen
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Contents
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Description:Summary: | Species: | Hu | | Applications: | WB, ELISA | | Clonality: | Monoclonal | | | Gene: | YWHAQ | | Purity: | protein G purified | | Host: | Mouse | | | Specificity: | Anti-human 14-3-3 beta mAb, clone J2E9, is derived from hybridization of mouse FO myeloma cells with spleen cells from BALB/c mice immunized with a recombinant human YWHAB protein. | | Publications: | Antibody has not yet been mentioned in a publication. | Details: | Clone: | J2E9 | | Isotype: | IgG2a | | Immunogen: | Recombinant human 14-3-3 beta (1-246aa) purified from E. coli | Gene Symbol: YWHAQ | Related Genes: | MAPT, TH, AKT1, PRNP, LAMC2, RAF1, MAPK1, CDC25C, PIK3CG, BCL2L1, PTK2B, CHEK1, GSTP1, ZHX2, PKA, HCLS1, MAPK8, CASP3, ZCCHC6, SPTB, MAPK3, RASGRF1, SNCA, CDK5, SRC, BCL2, PKC, EGF, INS, CDC2, APP, MAP3K5, MAPK14, GRN, PPP2R4, EPHB2, PIK3CA, PIK3CB, PIK3CD, TP53 | Background: The 14-3-3 family plays a key regulatory role in signal transduction, checkpoint control, apoptotic and nutrient-sensing pathways. 14-3-3 proteins are highly conserved and ubiquitously expressed. There are at least seven isoforms, beta, gamma, episilon, sigma, zeta, tau and eta that have been identified in mammals. The 14-3-3 beta, a subtype of the 14-3-3 proteins, was found in B Cells, brain and liver etc. This 14-3-3 beta has been shown to interact with RAF1 and CDC25 phosphatases, suggesting that it may play a role in linking mitogenic signaling and the cell cycle machinery. Species: | Reactivity: | This antibody is reactive against Human. | Applications: | Uses: | The antibody has been tested by ELISA and Western blot analysis to assure specificity and reactivity. | | Dilutions: | ELISA, Western Blot 1:500-1:1000, | | Concentrations: | 1.0 mg/ml | Packaging: | Buffer: | Phosphate-Buffered Saline (pH 7.4) | | Storage: | Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles. | | Preservative: | 0.1% Sodium Azide | | Limitations: | This product is for research use only and is not approved for use in humans or in clinical diagnosis. Products are guaranteed for 6 months from date of receipt, except for peptides and proteins which are guaranteed for 3 months. | |
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