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Description |
Unit |
Price
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납기 |
재고 |
DataSheet |
주문/견적 |
| LCA-23-310340 |
NB100-2140 |
14-3-3 Antibody//Human, Mouse,/Rabbit |
1/EA |
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문의 |
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Subject
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14-3-3 Antibody |
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Description
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/ Human, Mouse,/Rabbit |
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Clonality
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Poly |
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Company
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Novus biologicals |
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Application
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IHC-P, IP, Western Blot |
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Conjugation
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Immunogen
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Contents
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Description:Summary: | Species: | Rt, Mu, Hu | | Applications: | WB, IP, IHC | | Clonality: | Polyclonal | | | Gene: | YWHAQ | | Purity: | Immunogen affinity purified | | Host: | Rabbit | | | Specificity: | Broadly reactive among the 14-3-3 family. This recognizes alpha, beta, zeta (delta) and theta 14-3-3. | | Publications: | Antibody has not yet been mentioned in a publication. | Details: | Isotype: | IgG | | Immunogen: | Synthetic peptide mapping to the amino terminal domain of human 14-3-3. | | Localization: | Cytoplasmic | Gene Symbol: YWHAQ | Entrez: | 10971 (Human) | | Related Genes: | MAPT, TH, AKT1, PRNP, LAMC2, RAF1, MAPK1, CDC25C, PIK3CG, BCL2L1, PTK2B, CHEK1, GSTP1, ZHX2, PKA, HCLS1, MAPK8, CASP3, ZCCHC6, SPTB, MAPK3, RASGRF1, SNCA, CDK5, SRC, BCL2, PKC, EGF, INS, CDC2, APP, MAP3K5, MAPK14, GRN, PPP2R4, EPHB2, PIK3CA, PIK3CB, PIK3CD, TP53 | Background: 14-3-3 family of proteins is composed of seven isotypes, beta, gamma, zeta, epsilon, tau, eta, and sigma, that play critical roles in cell signaling events that control cell cycle progression, transcriptional alterations, and apoptosis (1-4). 14-3-3 proteins were the first signaling molecules to be identified as specific phosphoserine/threonine binding proteins (1). 14-3-3 can serve as a direct regulator of its target by altering the function of the protein (3). 14-3-3 protein targets include the signalling intermediates Raf, MEKK, PI-3 kinase and IRS-1, cell cycle proteins CDK2, Wee1, and Cdc25, and apoptosis proteins BAD and ASK-1 (3,4). Species: | Reactivity: | Cross-reacts with Human, Mouse and Rat. Not yet tested in other species. | Applications: | Uses: | This antibody is useful for Immunohistochemistry, Immunoprecipitation and Western Blot. | | Dilutions: | immunohistochemistry , immunoprecipitation , Western Blot 1/400 | | Concentrations: | 0.2 mg/ml | | Positive Controls: | 3 positive controls | Packaging: | Buffer: | 0.2% Gelatin, PBS | | Storage: | Store at 4C. Do not freeze. | | Preservative: | 0.1% Sodium Azide | | Limitations: | This product is for research use only and is not approved for use in humans or in clinical diagnosis. Products are guaranteed for 6 months from date of receipt, except for peptides and proteins which are guaranteed for 3 months. | |
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