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| Cat. No |
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Description |
Unit |
Price
(VAT별도) |
납기 |
재고 |
DataSheet |
주문/견적 |
| LCA-23-310347 |
NB100-2465 |
14-3-3 sigma Antibody//Human/Goat |
1/EA |
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문의 |
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Subject
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14-3-3 sigma Antibody |
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Description
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/ Human/Goat |
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Clonality
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Poly |
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Company
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Novus biologicals |
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Application
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IHC-P, PEP-ELISA, Western Blot |
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Conjugation
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Immunogen
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Contents
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Description:Summary: | Species: | Hu | | Applications: | PEP-ELISA, IHC-P, WB | | Clonality: | Polyclonal | | | Gene: | SFN | | Purity: | Immunogen affinity purified | | Host: | Goat | | | Publications: | Antibody has not yet been mentioned in a publication. | Details: | Isotype: | IgG | | Immunogen: | Synthetic peptide: C-DLHTLSEDSYKDST, representing the internal region of the human protein according to NP_006133.1 | Gene Symbol: SFN | Entrez: | 2810 (Human) | | Swiss Prot: | NP_006133.1 (Human) | | Related Genes: | TP53, CDKN1A, REXO2, CDKN2A, TCEAL1, D4S234E, MMP1, PAK3, YWHAQ, NFE2L2, AKT1, SLC12A9, MAPK1, TP63, CKAP4, TH, PTGS2, CCNB1, CDH1, BCL2, CASP3, TRIM25, GABPA, GSTP1, EGFR, SERPINB3, RARB, JUN, RASSF1, MMP3, CCND1, CDC2, MSLN, ERBB2, ESR1, BAX, PCNA, HDAC9, YWHAZ, MAPK8 | Background: Members of the 14-3-3 family of proteins are highly conserved proteins, localized in neurons, and are axonally transported to the nerve terminals. They are also present, at lower levels, in various other eukaryotic tissues. 14-3-3 proteins appear to play important roles in a variety of signal transduction pathways, including those involved in cell cycle regulation and cell survival. As 14-3-3 proteins bind to specific phosphoserine-containing sequences they are likely to have an important role in signaling pathways mediated by serine/threonine protein kinases. 14-3-3 sigma may be required for Raf-1 kinase activity and phosphorylation, among many other functions. Species: | Reactivity: | Human. Expected from sequence similarity: Mouse, Rat, Dog. | Applications: | Uses: | Peptide ELISA, Western Blot and Immunohistochemistry Paraffin. Approx. 28kDa band observed in Human Skin lysates. In paraffin embedded Human Skin shows strong nuclear staining in selected cells of the basal layer . | | Dilutions: | Western Blot 0.1-0.3ug/ml, Immunohistochemistry-Paraffin 2-3ug/ml, Peptide ELISA 1:64000 | | Concentrations: | 0.5 mg/ml | | Positive Controls: | 2 positive controls | Packaging: | Buffer: | Tris-saline containing [pH7.3] with 0.5% BSA | | Storage: | Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles. | | Preservative: | 0.02% Sodium Azide | | Limitations: | This product is for research use only and is not approved for use in humans or in clinical diagnosis. Products are guaranteed for 6 months from date of receipt, except for peptides and proteins which are guaranteed for 3 months. | |
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