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Description |
Unit |
Price
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납기 |
재고 |
DataSheet |
주문/견적 |
| LCA-23-310368 |
NLS598 |
5HT1B Receptor Antibody//Human/Rabbit |
1/EA |
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문의 |
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Subject
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5HT1B Receptor Antibody |
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Description
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/ Human/Rabbit |
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Clonality
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Poly |
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Company
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Novus biologicals |
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Application
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IHC-P |
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Conjugation
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Immunogen
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Contents
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Description:Summary: | Species: | Hu | | Applications: | IHC-P | | Clonality: | Polyclonal | | | Gene: | HTR1B | | Purity: | Immunogen affinity purified | | Host: | Rabbit | | | Specificity: | 5-HT1B Receptor | | Publications: | Antibody has been mentioned in at least 1 publication. | Details: | Immunogen: | Synthetic peptide [KLH conjugated] made to the 3rd cytoplasmic loop | | Localization: | Cell Membrane | Gene Symbol: HTR1B | Entrez: | 3351 (Human) | | Related Genes: | HTR1A, HTR2A, HTR1D, 5-HT3, HTR2C, MS4A1, PSMC2, SLC6A4, PSMC1, HTR4, MRPS12, HTR7, TNFRSF11A, HTR2B, PSMD13, PSMD3, THRSP, PSMD8, PSMD6, HTR1F, POMC, RPS12, PSMD1, L1CAM, STATH, TAC1, PSMC5, EEF1A1, PSMD11, HTR1E, HTR6, PSMC4, PRL, CALCA, S100A12, BDNF, SNAP25, EF-G, DIO2, ZACN | Background: 5-HT1B (5-HT1D beta), a Serotonin Receptor, inhibits neurotransmitter release from neuronal terminals. Knockout mutant mice lacking this receptor exhibit decreased anxiety, increased aggression, and augmented alcohol and cocaine consumption compared to controls. 5-HT1B receptors have been found to control areas of the human brain involved in migraine pain, bipolar disorder, and obsessive compulsive disorder. The 5-HT1B receptor has been reported to be expressed in a variety of neurons predominantly in the central nervous system. It has been suggested that Human 5-HT1B receptors are located somatodendritically on GABAergic and peptidergic caudate-putamen neurons which project to the substantia nigra and globus pallidus, where these receptors are presynaptic. 5-HT1B expression has also been seen in heart, blood vessels, and eye. Species: | Reactivity: | Human. There is 100 % rat identity and 100 % rat homology. There is 100 % mouse identity and 100 % mouse homology. | Applications: | Uses: | This antibody is useful for Immunohistochemistry-Paraffin. | | Dilutions: | Immunohistochemistry-Paraffin | | Concentrations: | 1.0 mg/ml | | Positive Controls: | 1 positive controls | Packaging: | Buffer: | PBS | | Storage: | Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles. | | Preservative: | 0.01% Sodium Azide | | Limitations: | This product is for research use only and is not approved for use in humans or in clinical diagnosis. Products are guaranteed for 6 months from date of receipt, except for peptides and proteins which are guaranteed for 3 months. | |
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