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Description |
Unit |
Price
(VAT별도) |
납기 |
재고 |
DataSheet |
주문/견적 |
| LCA-23-310381 |
NLS1116 |
5HT2C Receptor Antibody//Human/Rabbit |
1/EA |
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문의 |
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Subject
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5HT2C Receptor Antibody |
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Description
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/ Human/Rabbit |
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Clonality
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Poly |
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Company
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Novus biologicals |
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Application
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IHC-P, IHC-P |
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Conjugation
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Immunogen
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Contents
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Description:Summary: | Species: | Hu | | Applications: | IHC-P, IHC | | Clonality: | Polyclonal | | | Gene: | HTR2C | | Purity: | Immunogen affinity purified | | Host: | Rabbit | | | Specificity: | 5-HT2C Receptor | Details: | Immunogen: | 3rd cytoplasmic domain of human | Gene Symbol: HTR2C | Entrez: | 3358 (Human) | | Related Genes: | HTR2A, HTR1A, HTR1B, HTR2B, SLC6A4, HTR7, HTR4, 5-HT3, HTR6, POMC, HTR1D, PRL, DRD4, DIO2, TPH1, MAOA, BBS9, DIO3, LMOD1, HTR1F, HTR5A, HTR1E, BDNF, DRD3, NPY, TNFRSF11A, DRD2, SLC6A3, CRH, ARHGDIB, LEP, GT, ATP7A, MVK, MDK, COMT, CYP2D6, NF2, HSPG2, HTR5B | Background: 5-HT2C, a Serotonin Receptor previously termed 5-HT1C, activates phospholipase C, resulting in a transient increase in intracellular calcium and activation of protein kinase C. Mutant mice lacking functional 5-HT2C receptor are overweight due to abnormal feeding behavior and are prone to epileptic seizures. Therefore, agonists of the 5-HT2C receptor such as m-chlorophenylpiperazine (mCPP) may be potential drugs for the treatment of obesity. However, mCPP also has unpleasant side effects such as anxiety and nausea in humans. Most psychedelic drugs bind 5-HT2A and 5-HT2C receptors, and their hallucinogenicity correlates with binding affinity. Expression of the 5-HT2C receptor has been reported predominantly in brain, but also in spinal cord and lung. ESTs have been isolated from human, mouse, and rat brain libraries. Species: Applications: | Uses: | Immunohistochemistry of Formalin fixed paraffin embedded sections. | | Dilutions: | immunohistochemistry , Immunohistochemistry-Paraffin | | Concentrations: | 1.0 mg/ml | Packaging: | Buffer: | Phosphate buffered saline, pH 7.7 | | Storage: | Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles. | | Preservative: | 0.01% Sodium Azide | | Limitations: | This product is for research use only and is not approved for use in humans or in clinical diagnosis. Products are guaranteed for 6 months from date of receipt, except for peptides and proteins which are guaranteed for 3 months. | |
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