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Description |
Unit |
Price
(VAT별도) |
납기 |
재고 |
DataSheet |
주문/견적 |
| LCA-23-310384 |
NLS655 |
5HT4 Receptor Antibody//Human/Rabbit |
1/EA |
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문의 |
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Subject
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5HT4 Receptor Antibody |
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Description
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/ Human/Rabbit |
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Clonality
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Poly |
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Company
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Novus biologicals |
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Application
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IHC-P |
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Conjugation
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Immunogen
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Contents
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Description:Summary: | Species: | Hu | | Applications: | IHC-P | | Clonality: | Polyclonal | | | Gene: | HTR4 | | Purity: | Immunogen affinity purified | | Host: | Rabbit | | | Specificity: | 5-HT4 Receptor | Details: | Immunogen: | 3rd cytoplasmic domain of human | Gene Symbol: HTR4 | Entrez: | 3360 (Human) | | Related Genes: | 5-HT3, HTR2A, HTR1A, HTR7, TNFRSF11A, HTR1B, ADCY7, HTR2C, HTR6, HTR2B, CA1, POMC, TAC1, HTR1D, HTF, VIP, HTR1F, HTR5A, SLC6A4, DIO2, HTR1E, BBS9, BDNF, EFS, CALR, CALCA, CCK, TRH, PKA, LMOD1, S100A12, HTR3A, GPR151, MRGPRX1, LGR6, OXER1, VN1R17P, FZD4, MRGPRX3, MRGPRX4 | Background: The 5-HT4 receptor, a member of the Serotonin Receptor subfamily, has been shown to affect the sensory and motor functions of the gut. Some of the most promising emerging therapies in Irritable Bowel Syndrome revolve around targeted pharmacotherapeutic modulation of serotonin receptors (ie, 5-HT3 and 5-HT4 subtypes). At least 9 isoforms (5-HT4A-5-HT4G, and 5-HT4n) have been described, which differ in the length and composition of their intracellular C termini after a common splicing site (L358). A ninth isoform (5-HT4H) results in the insertion of 14 amino acids into the second intracellular loop. 5-HT4 receptor expression has been documented primarily in the brain, and in colon, heart, and vessel. An EST has been isolated from a human cancerous nerve library. Species: Applications: | Uses: | Immunohistochemistry of Formalin fixed paraffin embedded sections. | | Dilutions: | Immunohistochemistry-Paraffin | | Concentrations: | 1.0 mg/ml | Packaging: | Buffer: | Phosphate buffered saline, pH 7.7, | | Storage: | Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles. | | Preservative: | 0.01% Sodium Azide | | Limitations: | This product is for research use only and is not approved for use in humans or in clinical diagnosis. Products are guaranteed for 6 months from date of receipt, except for peptides and proteins which are guaranteed for 3 months. | |
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