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| Cat. No |
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Description |
Unit |
Price
(VAT별도) |
납기 |
재고 |
DataSheet |
주문/견적 |
| LCA-23-310400 |
NB100-65014 |
5-Methylcytidine Antibody (33D3)//Human, Mouse,/Mouse |
1/EA |
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문의 |
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Subject
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5-Methylcytidine Antibody (33D3) |
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Description
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/ Human, Mouse,/Mouse |
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Clonality
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Mono |
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Company
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Novus biologicals |
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Application
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FACS, IF, IHC-P, IHC-P |
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Conjugation
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Immunogen
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Contents
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Description:Summary: | Species: | Rt, Mu, Hu | | Applications: | IF, IHC-P, FACS, IHC-Fr | | Clonality: | Monoclonal | | | Purity: | Affinity purified | | Host: | Mouse | | | Specificity: | Recognizes the modified base 5-methylcytidine (5-MeCyd) found in DNA of plants and vertebrates. DNA methylation is a DNA modification process, which is involved in the control of gene expression. Reports suggest that in tumours, DNA is frequently globally hypomethylated compared to the DNA from normal tissue. Clone 33D3 has been developed to discriminate between the modified base 5-MeCyd and the normal counterpart cytosine. NB100-65014 has been reported for use in Methylated DNA immunoprecipitation (MeDIP). | | Publications: | Antibody has not yet been mentioned in a publication. | Details: | Clone: | 33D3 | | Isotype: | IgG1 | | Immunogen: | Made to Chemical 5-METHYLCYTIDINE | Background: Cytosine is a nucleobase whilst cytidine is a molecule (known as a nucleoside) that is formed when cytosine is attached to a ribose ring (also known as a ribofuranose) via a ß-N1-glycosidic bond. Recognizes the modified base 5-methylcytidine found in DNA of plants and vertebrates. DNA methylation is a DNA modification process, which is involved in the control of gene expression. Reports suggest that in tumors, DNA is frequently globally hypomethylated compared to the DNA from normal tissue. Species: | Reactivity: | Reacts with Human, Rat and Mouse. | Applications: | Uses: | Immunohistochemistry-Frozen and Paraffin, Flow cytometry / FACS analysis and Immunofluorescence This product requires antigen retrieval using heat treatment prior to staining of paraffin sections. Sodium citrate buffer pH6.0 is recommended for this purpose. | | Dilutions: | Immunohistochemistry-Frozen flow cytometry / FACS analysis Immunohistochemistry-Paraffin immunofluorescence | | Concentrations: | 1.0 mg/ml | Packaging: | Buffer: | Phosphate buffered saline pH7.4 | | Storage: | Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles. | | Preservative: | 0.01% Thimerosal | | Limitations: | This product is for research use only and is not approved for use in humans or in clinical diagnosis. Products are guaranteed for 6 months from date of receipt, except for peptides and proteins which are guaranteed for 3 months. | |
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