Swiss Prot Num | O60831 |
Immunogen | Synthetic peptide corresponding to aa 165-178 of human JM4 |
Product Type | Antibodies |
Storage | Store the antibody (undiluted) at 2 – 8 °C. Shelf life: One year from despatch. |
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Format | State: Liquid affinity purified g fraction |
? | Buffer System: 10 mM PBS, pH 7.4 with BSA and Sodium Azide |
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Specificity | This antibody detects JM4 at aa 165-178. |
Add. information | Molecular weight: 19 kDa Cellular localisation: Cytoplasmic and cell membrane |
Application | Immunohistochemistry on paraffin sections (1:100; 30 min at RT); staining of formalin-fixed tissues requires boiling tissue sections in 10 mM citrate buffer, pH 6.0 for 10 min followed by cooling at RT for 20 min. Positive control: Brain. |
Background | JM4 is a 19 kDa four-transmembrane protein binding to the CCR5 receptor. It plays a role in the regulation of intracellular protein transport. It is expressed in normal brain, small intestine, lung, spleen, and pancreas and has also been detected in tumors of breast, colon, lung, and ovary. |
Concentration | 0.2 mg/ml |