|
| |
| Cat. No |
Model |
Description |
Unit |
Price
(VAT별도) |
납기 |
재고 |
DataSheet |
주문/견적 |
| LCA-24-372745 |
AP15568PU-N |
G.D.N.F//Human, Mouse, Rat/Rabbit |
1/EA |
|
|
|
 |
문의 |
|
|
|
|
|
|
|
Subject
|
G.D.N.F |
|
Description
|
/ Human, Mouse, Rat/Rabbit |
|
Clonality
|
Mono |
|
Company
|
Acris Antibodies GmbH |
|
Application
|
Paraffin Sections |
|
Conjugation
|
|
|
Immunogen
|
|
|
Contents
|
Description: | Manufacturer | Acris Antibodies GmbH | | Quantity | 1.0 ml | | Reactivity | Human, Mouse, Rat | | Presentation | Purified | | Applications | Paraffin Sections | | Host | Rabbit | | Shipping to | Worldwide | | Swiss Prot Num | P39905 | | Immunogen | Synthetic peptide corresponding to aa 186-205 of human GDNF | | Product Type | Antibodies | | Storage | Store the antibody (undiluted) at 2 – 8 °C. Shelf life: One year from despatch. | |
| Format | State: Liquid affinity purified Ig fraction | | ? | Buffer System: 10 mM PBS, pH 7.4 with BSA and Sodium Azide | |
| Specificity | This antibody detects G.D.N.F (aa 186-205). | | Add. information | Molecular weight: 15 kDa Cellular localisation: Cytoplasmic | | Application | Immunohistochemistry on paraffin sections (1:100, 10 min at RT); staining of formalin-fixed tissues requires boiling tissue sections in 10mM citrate buffer, pH 6.0 for 10 min followed by cooling at RT for 20 min. Positive control: Brain tumor. Hippocampus. | | Background | Glial cell line-derived neurotrophic factor (GDNF) has been identified as a potent neurotrophic factor that enhances survival of midbrain dopaminergic neurons. GDNF promotes the survival and morphological differentiation of dopaminergic neurons and increases their high-affinity dopamine uptake. It was suggested that GDNF may have utility in the treatment of Parkinson's disease, which is marked by progressive degeneration of midbrain dopaminergic neurons. | | Concentration | 0.2 mg/ml | |
|
|
|
|
