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| Cat. No |
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Description |
Unit |
Price
(VAT별도) |
납기 |
재고 |
DataSheet |
주문/견적 |
| LCA-24-372749 |
AP15569PU-N |
Gab-1//Human, Mouse, Rat, Monkey/Rabbit |
1/EA |
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문의 |
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Subject
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Gab-1 |
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Description
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/ Human, Mouse, Rat, Monkey/Rabbit |
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Clonality
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Mono |
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Company
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Acris Antibodies GmbH |
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Application
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Paraffin Sections, Western blot / Immunoblot, Immunoprecipitation |
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Conjugation
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Immunogen
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Contents
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Description: | Manufacturer | Acris Antibodies GmbH | | Quantity | 1.0 ml | | Reactivity | Human, Mouse, Rat, Monkey | | Presentation | Purified | | Applications | Paraffin Sections, Western blot / Immunoblot, Immunoprecipitation | | Host | Rabbit | | Shipping to | Worldwide | | Swiss Prot Num | Q13480 | | Immunogen | A synthetic peptide from C-terminal of human Gab-1. | | Product Type | Antibodies | | Storage | Store the antibody undiluted at 2-8°C. DO NOT FREEZE! Shelf life: one year from despatch. | |
| Format | State: Liquid purified Ig | | ? | Buffer System: 10mM PBS, pH 7.4 with BSA and Sodium Azide | |
| Specificity | This antibody reacts to GAB1. | | Application | Western Blotting. Immunoprecipitation. Immunohistochemistry on paraffin sections: 1/50 for 10 min at RT; Staining of formalin-fixed tissues requires boiling tissue sections in 10mM citrate buffer, pH 6.0 for 10 min followed by cooling at RT for 20 min. Positive Control: 293 cells. Astrocytoma. | | Background | Gab-1 is a multisubstrate docking protein downstream in the signaling pathways of different receptor tyrosine kinases, including the epidermal growth factor receptor (EGFR) and appears to play a crucial role in cellular growth response, transformation, and apoptosis. Experimental data indicates that Gab1 coupling to the Met receptor requires binding of Grb2 and correlates with the transforming potential of Tpr-Met. | | Concentration | 0,2 mg/ml | |
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