| Synonyms | GRB2-associated binder 1 |
| Swiss Prot Num | Q13480 |
| Immunogen | This antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding Y259 of human GAB1. |
| Product Type | Antibodies |
| Storage | Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch. |
| References | 1. Guo A, et al. (2008) Proc Natl Acad Sci U S A 105, 692-7 2. Rikova K, et al. (2007) Cell 131, 1190-203 3. Goss VL, et al. (2006) Blood 107, 4888-97 4. Wolf-Yadlin A, et al. (2006) Mol Syst Biol 2, 54 5. Salomon AR, et al. (2003) Proc Natl Acad Sci U S A 100, 443-8 |
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| Format | State: Liquid purified Ig fraction. |
| ? | Purification: Protein A Chromatography followed by two-step phosphospecific peptide affinity purification. |
| ? | Buffer System: PBS with 0.09% (W/V) Sodium Azide as preservative. |
|
| Specificity | This antibody detects GAB1 pTyr259. |
| Add. information | Molecular weight: 76485 Da |
| Application | ELISA: 1/1,000. Dot Blot: 1/500. |
| Background | Gab1 is a member of the IRS1-like multisubstrate docking protein family. It is an important mediator of branching tubulogenesis and plays a central role in cellular growth response, transformation and apoptosis. |
| Caution | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Concentration | 0.25 mg/ml |
