Synonyms | GRB2-associated-binding protein 1; Growth factor receptor bound protein 2-associated protein 1; GRB2-associated binder 1 |
Swiss Prot Num | Q13480 |
Immunogen | This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide corresponding to amino acid residues surrounding Y627 of human GAB1. |
Product Type | Antibodies |
Storage | Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch. |
References | 1. Seiden-Long,I., Carcinogenesis 29 (3), 647-655 (2008) 2. Oka,M., J. Invest. Dermatol. 128 (1), 188-195 (2008) 3. Laramee,M., J. Biol. Chem. 282 (11), 7758-7769 (2007) |
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Format | State: Liquid purified Ig |
? | Purification: Protein A column, followed by peptide affinity purification |
? | Buffer System: PBS with 0.09% (W/V) sodium azide |
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Specificity | This antibody reacts to GAB1. |
Application | ELISA: 1/1,000. Immunohistochemistry: 1/10 - 1/50. |
Background | GAB1 is a member of the IRS1-like multisubstrate docking protein family. It is an important mediator of branching tubulogenesis and plays a central role in cellular growth response, transformation and apoptosis. |
Caution | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
Concentration | 0.25 mg/ml |