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Cat. No |
Model |
Description |
Unit |
Price (VATº°µµ) |
³³±â |
Àç°í |
DataSheet |
ÁÖ¹®/°ßÀû |
LCA-24-372762 |
AP05918PU-N |
GABA A Receptor//Human, Mouse, Rat, Canine, Monkey/Rabbit |
1/EA |
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¹®ÀÇ |
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Subject
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GABA A Receptor |
Description
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/ Human, Mouse, Rat, Canine, Monkey/Rabbit |
Clonality
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Mono |
Company
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Acris Antibodies GmbH |
Application
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Western blot / Immunoblot |
Conjugation
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Immunogen
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Contents
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Description: Manufacturer | Acris Antibodies GmbH | Quantity | 0.1 ml | Reactivity | Human, Mouse, Rat, Canine, Monkey | Presentation | Purified | Applications | Western blot / Immunoblot | Isotype | IgG | Host | Rabbit | Shipping to | Worldwide | Synonyms | Review 022 | Swiss Prot Num | P63138 | Immunogen | Fusion protein within the cytosolic loop of rat GABA A receptor beta 2 subunit. | Product Type | Antibodies | Storage | Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch. | References | 1. Burt, D.R. et al. (1991) GABAA receptor subtypes: from pharmacology to molecular biology. FASEB. J. 5: 2916 - 2923. | |
Format | State: Liquid purified Ig | ? | Purification: Affinity chromatography | ? | Buffer System: 10mM HEPES, pH7.5 containing 0.09% Sodium Azide, 0.01% Bovine Serum Albumin and 50% Glycerol | |
Specificity | This antibody is specific for the beta 2 subunit of rat gamma-aminobutyric acid A (GABA A) receptor. | Application | Western Blot: 1:1000; detects a band of approximately 50 to 56 kDa in rat cerebellum lysates. | Background | GABA A receptors are GABA gated chloride channels, which are important mediators of neuronal inhibition in the mammalian central nervous system. Activation of the GABA A site results in increased intracellular chloride concentration and hyperpolarization of the cell. GABA A receptors are pentameric structures assembled from a family of distinct subunits. At least fourteen distinct subunits have been identified, which show distinct patterns of temporal and spatial expression. GABA A receptors may be modulated by several drug types including benzodiazepines and barbiturates, and by phosphorylation by protein kinase C (PKC) and protein kinase A (PKA). | Caution | (A full Health and Safety assessment is available upon request) This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only. | Review | r022 GABA A Receptor Regulator of Excitability and Drug Ta | |
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